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Cellosaurus ES6 (CVCL_1202)

Cell line name ES6
Synonyms ES-6
Accession CVCL_1202
Resource Identification Initiative To cite this cell line use: ES6 (RRID:CVCL_1202)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Sequence variations STAG2 p.Leu264Pro (PubMed=25010205).
Disease Ewing sarcoma (NCIt: C4817)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; PubMed=25010205

Markers:
AmelogeninX,Y
CSF1PO12
D13S31711,13
D16S53912
D18S5115
D19S43312,15
D21S1129
D2S133822,25
D5S81811,13
D7S82011,12
D8S117911,14
FGA18,22
TH017
TPOX8,9
vWA15
Publications

PubMed=25010205; DOI=10.1371/journal.pgen.1004475
Brohl A.S., Solomon D.A., Chang W., Wang J., Song Y., Sindiri S., Patidar R., Hurd L., Chen L., Shern J.F., Liao H., Wen X., Gerard J., Kim J.-S., Lopez Guerrero J.A., Machado I., Wai D.H., Picci P., Triche T.J., Horvai A.E., Miettinen M., Wei J.S., Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.
The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutation.
PLoS Genet. 10:E1004475-E1004475(2014)

PubMed=26351324; DOI=10.1158/1535-7163.MCT-15-0074
Teicher B.A., Polley E., Kunkel M., Evans D., Silvers T.E., Delosh R.M., Laudeman J., Ogle C., Reinhart R., Selby M., Connelly J., Harris E., Monks A., Morris J.
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Mol. Cancer Ther. 14:2452-2462(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line databases/resources CCLE; ES6_BONE
Cosmic-CLP; 949157
GDSC; 949157
LINCS_LDP; LCL-1443
Chemistry resources ChEMBL-Cells; CHEMBL3308152
ChEMBL-Targets; CHEMBL2366373
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669773
GEO; GSM1676357
GEO; GSM1701687
Other Wikidata; Q54832643
Polymorphism and mutation databases Cosmic; 684058
Cosmic; 949157
Cosmic; 2228225