Cellosaurus ETK-1 (CVCL_1206)

Cell line name ETK-1
Synonyms ETK1
Accession CVCL_1206
Resource Identification Initiative To cite this cell line use: ETK-1 (RRID:CVCL_1206)
Comments Problematic cell line: Contaminated. Shown to be a SSP-25 derivative (PubMed=16643607, PubMed=20143388).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4902 (SSP-25)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Web pages http://iclac.org/wp-content/uploads/Cross-Contaminations-v8_0.pdf

PubMed=10761710; DOI=10.1111/j.1349-7006.2000.tb00935.x
Enjoji M., Nakashima M., Nakamuta M., Nawata H.
Transforming growth factor-alpha induces the differentiation of sarcomatoid cholangiocarcinoma cells.
Jpn. J. Cancer Res. 91:223-230(2000)

PubMed=16643607; DOI=10.1111/j.1749-0774.2005.00007.x
Yoshino K., Iimura E., Saijo K., Iwase S., Fukami K., Ohno T., Obata Y., Nakamura Y.
Essential role for gene profiling analysis in the authentication of human cell lines.
Hum. Cell 19:43-48(2006)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections RCB; RCB1289 - Discontinued
Cell line databases/resources Cosmic-CLP; 906861
GDSC; 906861
Biological sample resources BioSample; SAMN03151925
Chemistry resources ChEMBL-Cells; CHEMBL3308831
ChEMBL-Targets; CHEMBL2366116
Gene expression databases GEO; GSM1669779
Polymorphism and mutation databases Cosmic; 906861