Home  |  Contact

Cellosaurus EW-12 (CVCL_1210)

[Text version]

Cell line name EW-12
Synonyms EW12; IARC-EW12; IARC-EW-12; IARC-EW 12
Accession CVCL_1210
Resource Identification Initiative To cite this cell line use: EW-12 (RRID:CVCL_1210)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Homozygous for TP53 p.Arg273Cys (c.817C>T) (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African21.92
Native American0
East Asian, North2.41
East Asian, South0.17
South Asian6.25
European, North15.31
European, South53.94
Disease Ewing sarcoma (NCIt: C4817)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S82010
D13S31711
D16S53912
TH019
TPOX8
vWA15,20

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; EW12_BONE
Cell_Model_Passport; SIDM00200
Cosmic-CLP; 949162
DepMap; ACH-002112
GDSC; 949162
Chemistry resources ChEMBL-Cells; CHEMBL3308528
ChEMBL-Targets; CHEMBL2366255
PharmacoDB; EW12_352_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669783
Other Wikidata; Q54832991
Polymorphism and mutation databases Cosmic; 684063
Cosmic; 949162
IARC_TP53; 27163
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number19