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Cellosaurus GA-10 clone 20 (CVCL_1223)

[Text version]

Cell line name GA-10 clone 20
Synonyms GA-10 (Clone 20); GA-10-Clone-20
Accession CVCL_1223
Resource Identification Initiative To cite this cell line use: GA-10 clone 20 (RRID:CVCL_1223)
Comments Characteristics: EBV-negative.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro152Leu (c.455C>T); ClinVar=VCV000142766; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ile232Asn (c.695T>A); ClinVar=VCV000850008; Zygosity=Heterozygous (from parent cell line).
Disease Adult Burkitt leukemia (NCIt: C7954)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1222 (GA-10)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO10
D5S81811
D7S8208,10
D13S31711
D16S53911,12
TH019,9.3
TPOX8,11
vWA16,20

Run an STR similarity search on this cell line
Publications

PubMed=11482875; DOI=10.1006/bcmd.2001.0428
Rapoport A.P., Simons-Evelyn M., Chen T., Sidell R., Luhowskyj S., Rosell K., Obrig T., Hicks D., Hinkle P.M., Nahm M., Insel R.A., Abboud C.N.
Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt's lymphoma cell line containing mutant p53 genes.
Blood Cells Mol. Dis. 27:610-624(2001)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references
Cell line collections ATCC; CRL-2394
Cell line databases/resources CLO; CLO_0003440
Cell_Model_Passport; SIDM01255
LINCS_LDP; LCL-2035
Encyclopedic resources Wikidata; Q54835416
Gene expression databases ArrayExpress; E-MTAB-783
Polymorphism and mutation databases Cosmic; 906866
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number21