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Cellosaurus GA-10 clone 4 (CVCL_1224)

[Text version]

Cell line name GA-10 clone 4
Synonyms GA-10 (Clone 4); GA-10-Clone-4
Accession CVCL_1224
Resource Identification Initiative To cite this cell line use: GA-10 clone 4 (RRID:CVCL_1224)
Comments Characteristics: EBV-negative.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations Heterozygous for TP53 p.Pro152Leu (c.455C>T) and p.Ile232Asn (c.695T>A) (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1222 (GA-10)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO10
D5S81811
D7S8208,10
D13S31711
D16S53911,12
TH019,9.3
TPOX8,11
vWA16,20

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Publications

PubMed=11482875; DOI=10.1006/bcmd.2001.0428
Rapoport A.P., Simons-Evelyn M., Chen T., Sidell R., Luhowskyj S., Rosell K., Obrig T., Hicks D., Hinkle P.M., Nahm M., Insel R.A., Abboud C.N.
Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt's lymphoma cell line containing mutant p53 genes.
Blood Cells Mol. Dis. 27:610-624(2001)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references
Cell line collections ATCC; CRL-2393
Cell line databases/resources Cell_Model_Passport; SIDM01252
Ontologies CLO; CLO_0003441
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669802
Other Wikidata; Q54835417
Polymorphism and mutation databases Cosmic; 687841
Cosmic; 906867
IARC_TP53; 21336
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number16