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Cellosaurus GA-10 clone 4 (CVCL_1224)

[Text version]

Cell line name GA-10 clone 4
Synonyms GA-10 (Clone 4); GA-10-Clone-4
Accession CVCL_1224
Resource Identification Initiative To cite this cell line use: GA-10 clone 4 (RRID:CVCL_1224)
Comments Characteristics: EBV-negative.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro152Leu (c.455C>T); ClinVar=VCV000142766; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ile232Asn (c.695T>A); ClinVar=VCV000850008; Zygosity=Heterozygous (from parent cell line).
Disease Adult Burkitt leukemia (NCIt: C7954)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1222 (GA-10)
Sex of cell Male
Age at sampling 41Y
Category Cancer cell line
STR profile Source(s): ATCC


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PubMed=11482875; DOI=10.1006/bcmd.2001.0428
Rapoport A.P., Simons-Evelyn M., Chen T., Sidell R., Luhowskyj S., Rosell K., Obrig T., Hicks D., Hinkle P.M., Nahm M., Insel R.A., Abboud C.N.
Flavopiridol induces apoptosis and caspase-3 activation of a newly characterized Burkitt's lymphoma cell line containing mutant p53 genes.
Blood Cells Mol. Dis. 27:610-624(2001)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cell line collections ATCC; CRL-2393
Cell line databases/resources CLO; CLO_0003441
Cell_Model_Passport; SIDM01252
Chemistry resources PharmacoDB; GA10Clone4_396_2019
Encyclopedic resources Wikidata; Q54835417
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1669802
Polymorphism and mutation databases Cosmic; 687841
Cosmic; 906867
IARC_TP53; 21336
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number23