Cellosaurus GAK (CVCL_1225)

Cell line name GAK
Accession CVCL_1225
Resource Identification Initiative To cite this cell line use: GAK (RRID:CVCL_1225)
Comments Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Vulvar melanoma (NCIt: C40329)
Derived from metastatic site: Inguinal lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D13S3179,13
D16S53912
D18S5113
D19S43314,15
D21S1129,30
D2S133818,20
D3S135816
D5S81810
D7S82011
D8S117910,11
FGA24
Penta D9,11
Penta E9,10
TH017
TPOX8,9
vWA15,18
Publications

PubMed=6431036
Nozawa S., Ohta H., Tsukazaki K., Udagawa Y., Kurihara S., Kano S.
A newly established melanoma cell line (GAK) with 5-S-cysteinyldopa phenotype.
Nippon Sanka Fujinka Gakkai Zasshi 36:883-892(1984)

PubMed=15467732; DOI=10.1038/sj.onc.1208152
Tanami H., Imoto I., Hirasawa A., Yuki Y., Sonoda I., Inoue J., Yasui K., Misawa-Furihata A., Kawakami Y., Inazawa J.
Involvement of overexpressed wild-type BRAF in the growth of malignant melanoma cell lines.
Oncogene 23:8796-8804(2004)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections IFO; IFO50321
JCRB; JCRB0180
Cell line databases/resources CGH-DB; 9290-4
Cosmic-CLP; 910932
GDSC; 910932
LINCS_LDP; LCL-1272
Biological sample resources BioSample; SAMN03472868
Chemistry resources ChEMBL-Cells; CHEMBL3308154
ChEMBL-Targets; CHEMBL2366301
Gene expression databases GEO; GSM1669803
Polymorphism and mutation databases Cosmic; 905204
Cosmic; 910932
Cosmic; 1995410