Cellosaurus GDM-1 (CVCL_1230)

Cell line name GDM-1
Synonyms GDM1
Accession CVCL_1230
Resource Identification Initiative To cite this cell line use: GDM-1 (RRID:CVCL_1230)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~40-50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Misspelling: GMD-1; In Cosmic 2131537.
Derived from sampling site: Peripheral blood.
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX
CSF1PO12
D13S31711,12
D16S53912
D18S5112,13
D21S1129
D3S135814,15
D5S81813
D7S82011,12
D8S117914,16
FGA22,23
Penta D8,11
Penta E15,20
TH016
TPOX8,11
vWA16,17
Publications

PubMed=6296552; DOI=10.1016/0145-2126(82)90055-8
Ben-Bassat H., Korkesh A., Voss R., Leizerowitz R., Polliack A.
Establishment and characterization of a new permanent cell line (GDM-1) from a patient with myelomonoblastic leukemia.
Leuk. Res. 6:743-752(1982)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=23955599; DOI=10.1038/ng.2731
Kon A., Shih L.-Y., Minamino M., Sanada M., Shiraishi Y., Nagata Y., Yoshida K., Okuno Y., Bando M., Nakato R., Ishikawa S., Sato-Otsubo A., Nagae G., Nishimoto A., Haferlach C., Nowak D., Sato Y., Alpermann T., Nagasaki M., Shimamura T., Tanaka H., Chiba K., Yamamoto R., Yamaguchi T., Otsu M., Obara N., Sakata-Yanagimoto M., Nakamaki T., Ishiyama K., Nolte F., Hofmann W.K., Miyawaki S., Chiba S., Mori H., Nakauchi H., Koeffler H.P., Aburatani H., Haferlach T., Shirahige K., Miyano S., Ogawa S.
Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.
Nat. Genet. 45:1232-1237(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-2627
DSMZ; ACC-87
ICLC; HTL01008
Cell line databases/resources CLDB; cl1446
CLDB; cl5541
CCLE; GDM1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
CGH-DB; 9221-4
Cosmic-CLP; 906870
GDSC; 906870
IGRhCellID; GDM1
LINCS_LDP; LCL-1052
Ontologies CLO; CLO_0003467
EFO; EFO_0002183
Biological sample resources BioSample; SAMN03473160
Chemistry resources ChEMBL-Cells; CHEMBL3308198
ChEMBL-Targets; CHEMBL2366157
Gene expression databases GEO; GSM887023
GEO; GSM888093
GEO; GSM1446735
GEO; GSM1669808
Polymorphism and mutation databases Cosmic; 787430
Cosmic; 906870
Cosmic; 975249
Cosmic; 999777
Cosmic; 1012067
Cosmic; 1177802
Cosmic; 1197932
Cosmic; 1281313
Cosmic; 2089666
Cosmic; 2131537
Cosmic; 2306196