Cell line name | H9 | ||||||||||||||||||||||
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Synonyms | HT clone H9; HT(H9); H 9; H-9 | ||||||||||||||||||||||
Accession | CVCL_1240 | ||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: H9 (RRID:CVCL_1240) | ||||||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Population: Caucasian. Characteristics: Permissive for HIV-1 replication. Is accordingly used to isolate and propagate HIV-1 from the blood of patients with AIDS. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Anecdotal: For a number of years it was not known that H9 used by Gallo's lab to isolate HIV-1 (HTLV-III) was in fact a clone of Hut 78 from Minna's lab (PubMed=2567177). This created a controversy between the labs of Minna and Gallo (PubMed=2193399). Discontinued: IZSLER; BS TCL 19; probable. Derived from sampling site: Peripheral blood. Cell type=T-cell. | ||||||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Sezary syndrome (NCIt: C3366) Sezary syndrome (ORDO: Orphanet_3162) | ||||||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Hierarchy | Parent: CVCL_0337 (HuT 78) Children:
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Sex of cell | Male | ||||||||||||||||||||||
Age at sampling | 53Y | ||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP; ECACC; KCLB Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||
Web pages | http://www.nibsc.org/Default.aspx?pageid=597&id=0001&theme=default http://www.bmj.com/rapid-response/2011/10/30/cell-lines-hut102-and-hut78 | ||||||||||||||||||||||
Publications | PubMed=2567177; DOI=10.1089/aid.1989.5.253 PubMed=2193399; DOI=10.1126/science.2193399 PubMed=1460674; DOI=10.1093/jnci/84.24.1922 PubMed=8320746; DOI=10.1093/jnci/85.14.1168 PubMed=8127147 PubMed=8641406; DOI=10.1111/j.1600-0609.1996.tb00721.x PubMed=17170727; DOI=10.1038/sj.leu.2404486 PubMed=20164919; DOI=10.1038/nature08768 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 | ||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||
Cell line collections | ATCC; HTB-176
CCTCC; GDC0031 ECACC; 85050301 HIVReagentProgram; ARP-87 ICLC; HTL05006 IZSLER; BS TCL 19 KCB; KCB 200418YJ KCLB; 30176 | ||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0003581
CLO; CLO_0003612 CLDB; cl1556 CLDB; cl1557 CLDB; cl7167 CCRID; 4201MOU-CCTCC00031 Cell_Model_Passport; SIDM01251 Cosmic-CLP; 907043 DepMap; ACH-002240 LINCS_LDP; LCL-1144 Lonza; 910 TOKU-E; 3613 | ||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0001944 | ||||||||||||||||||||||
Biological sample resources | BioSample; SAMN03472731 | ||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308402
ChEMBL-Targets; CHEMBL614806 GDSC; 907043 PharmacoDB; H9_439_2019 | ||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54872230 | ||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0003045 | ||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM1669836 | ||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687842
Cosmic; 907043 Cosmic; 933542 Cosmic; 2301568 Cosmic; 2668295 IARC_TP53; 21356 | ||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||||||
Entry history | |||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||
Last entry update | 16-Dec-2021 | ||||||||||||||||||||||
Version number | 30 |