Cellosaurus HAL-01 (CVCL_1242)

Cell line name HAL-01
Synonyms HAL01; HAL-1
Accession CVCL_1242
Resource Identification Initiative To cite this cell line use: HAL-01 (RRID:CVCL_1242)
Comments Part of: COSMIC cell lines project.
Doubling time: 32 hours (PubMed=2027299); ~48 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Derived from sampling site: Peripheral blood.
Disease B acute lymphoblastic leukemia (NCIt: C8644)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 17Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; RCB


Ohyashiki K., Fujieda H., Miyauchi J., Ohyashiki J.H., Tauchi T., Saito M., Nakazawa S., Abe K., Yamamoto K., Clark S.C., Toyama K.
Establishment of a novel heterotransplantable acute lymphoblastic leukemia cell line with a t(17;19) chromosomal translocation the growth of which is inhibited by interleukin-3.
Leukemia 5:322-331(1991)

PubMed=9680106; DOI=10.1016/S0145-2126(98)00050-2
Matsuo Y., Drexler H.G.
Establishment and characterization of human B cell precursor-leukemia cell lines.
Leuk. Res. 22:567-579(1998)

Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Taketani T., Taki T., Sugita K., Furuichi Y., Ishii E., Hanada R., Tsuchida M., Sugita K., Ida K., Hayashi Y.
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections DSMZ; ACC-610
KCB; KCB 94011YJ
RCB; RCB0540
Cell line databases/resources Cosmic-CLP; 949153
GDSC; 949153
Ontologies BTO; BTO:0004942
CLO; CLO_0050976
Biological sample resources BioSample; SAMN01821626
BioSample; SAMN03473501
Chemistry resources ChEMBL-Cells; CHEMBL3308233
ChEMBL-Targets; CHEMBL2366142
Gene expression databases GEO; GSM1669838
Polymorphism and mutation databases Cosmic; 949153
Cosmic; 996300
Cosmic; 998738
Cosmic; 999742
Cosmic; 1037744