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Cellosaurus HAL-01 (CVCL_1242)

[Text version]

Cell line name HAL-01
Synonyms HAL01; HAL-1
Accession CVCL_1242
Resource Identification Initiative To cite this cell line use: HAL-01 (RRID:CVCL_1242)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 32 hours (PubMed=2027299); ~48 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.89
East Asian, North78.59
East Asian, South19.2
South Asian0
European, North0
European, South1.33
Disease B acute lymphoblastic leukemia (NCIt: C8644)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 17Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; RCB

Markers:
AmelogeninX
CSF1PO11,12
D5S81812,13
D7S82010,12
D13S31711
D16S5399,11
TH016,8
TPOX8,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=2027299
Ohyashiki K., Fujieda H., Miyauchi J., Ohyashiki J.H., Tauchi T., Saito M., Nakazawa S., Abe K., Yamamoto K., Clark S.C., Toyama K.
Establishment of a novel heterotransplantable acute lymphoblastic leukemia cell line with a t(17;19) chromosomal translocation the growth of which is inhibited by interleukin-3.
Leukemia 5:322-331(1991)

DOI=10.11418/jtca1981.15.4_211
Matsuo Y., Okochi A., Ariyasu T., Iimura E., Ohno T.
Identification of cell lines with variable numbers of tandem repeat (VNTR) amplified by polymerase chain reaction.
Tissue Cult. Res. Commun. 15:211-219(1996)

PubMed=9680106; DOI=10.1016/S0145-2126(98)00050-2
Matsuo Y., Drexler H.G.
Establishment and characterization of human B cell precursor-leukemia cell lines.
Leuk. Res. 22:567-579(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

PubMed=14504097; DOI=10.1182/blood-2003-02-0418
Taketani T., Taki T., Sugita K., Furuichi Y., Ishii E., Hanada R., Tsuchida M., Sugita K., Ida K., Hayashi Y.
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy.
Blood 103:1085-1088(2004)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections DSMZ; ACC-610
KCB; KCB 94011YJ
RCB; RCB0540
Cell line databases/resources CCLE; HAL01_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM00289
Cosmic-CLP; 949153
DepMap; ACH-002241
GDSC; 949153
LINCS_LDP; LCL-1046
Ontologies BTO; BTO:0004942
CLO; CLO_0050976
Biological sample resources BioSample; SAMN01821626
BioSample; SAMN03473501
Chemistry resources ChEMBL-Cells; CHEMBL3308233
ChEMBL-Targets; CHEMBL2366142
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669838
Other Wikidata; Q54872387
Polymorphism and mutation databases Cosmic; 949153
Cosmic; 996300
Cosmic; 998738
Cosmic; 999742
Cosmic; 1037744
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number23