Cellosaurus HD-MY-Z (CVCL_1273)

Cell line name HD-MY-Z
Synonyms HD-MyZ; HDMYZ
Accession CVCL_1273
Resource Identification Initiative To cite this cell line use: HD-MY-Z (RRID:CVCL_1273)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~35 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Pleural effusion.
Disease Hodgkin lymphoma (NCIt: C9357)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX,Y
CSF1PO11
D13S3178,11
D16S53911,14
D5S81811
D7S8209,11
TH019
TPOX10,11
vWA17
Publications

PubMed=8386741; DOI=10.1084/jem.177.5.1257
Bargou R.C., Mapara M.Y., Zugck C., Daniel P.T., Pawlita M., Dohner H., Dorken B.
Characterization of a novel Hodgkin cell line, HD-MyZ, with myelomonocytic features mimicking Hodgkin's disease in severe combined immunodeficient mice.
J. Exp. Med. 177:1257-1268(1993)

DOI=10.1159/000425254
Bargou R.C., Mapara M.Y., Arnold W., Daniel P.T., Dorken B.
Xenotransplantation of a novel Hodgkin cell line HD-MyZ into SCID mice.
(In) Immunodeficient animals: models for cancer research. Contributions in Oncology, Vol. 51; Arnold W., Kopf-Maier P., Michael B. (eds.); pp.187-192; Karger; Basel (1996)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-346
Cell line databases/resources CCLE; HDMYZ_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 907050
GDSC; 907050
IGRhCellID; HDMYZ
LINCS_LDP; LCL-2008
Ontologies CLO; CLO_0003672
EFO; EFO_0002190
Biological sample resources BioSample; SAMN03473357
Chemistry resources ChEMBL-Cells; CHEMBL3308544
ChEMBL-Targets; CHEMBL2366322
Gene expression databases GEO; GSM887065
GEO; GSM888135
GEO; GSM1669871
Polymorphism and mutation databases Cosmic; 907050
Cosmic; 1086356
Cosmic; 1278833