Cellosaurus HH [Human lymphoma] (CVCL_1280)

Cell line name HH [Human lymphoma]
Accession CVCL_1280
Resource Identification Initiative To cite this cell line use: HH [Human lymphoma] (RRID:CVCL_1280)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~50-70 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Omics: Virome analysis using RNAseq.
Derived from sampling site: Peripheral blood.
Disease Cutaneous T-cell non-Hodgkin lymphoma (NCIt: C3467)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO11,12
D13S31711,12
D16S53912
D5S81811,13
D7S82010
TH019
TPOX8,11
vWA15,16
Publications

PubMed=1879969; DOI=10.1002/ijc.2910490218
Starkebaum G., Loughran T.P. Jr., Waters C.A., Ruscetti F.W.
Establishment of an IL-2 independent, human T-cell line possessing only the p70 IL-2 receptor.
Int. J. Cancer 49:246-253(1991)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25355872; DOI=10.1128/JVI.02570-14
Cao S., Strong M.J., Wang X., Moss W.N., Concha M., Lin Z., O'Grady T., Baddoo M., Fewell C., Renne R., Flemington E.K.
High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project.
J. Virol. 89:713-729(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-2105
BCRC; 60248
DSMZ; ACC-707
Cell line databases/resources CCLE; HH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 907056
GDSC; 907056
IGRhCellID; HH
LINCS_LDP; LCL-1141
Ontologies CLO; CLO_0003744
EFO; EFO_0002194
Biological sample resources BioSample; SAMN03472543
Chemistry resources ChEMBL-Cells; CHEMBL3308142
ChEMBL-Targets; CHEMBL2366310
Gene expression databases GEO; GSM887082
GEO; GSM888152
GEO; GSM1669882
Polymorphism and mutation databases Cosmic; 687843
Cosmic; 907056
Cosmic; 1551452
Cosmic; 2153071
Cosmic; 2402471