Cellosaurus HO-1-N-1 (CVCL_1284)

Cell line name HO-1-N-1
Synonyms Ho-1-N-1; HO1-N-1; HO1-N1; Nakata-1
Accession CVCL_1284
Resource Identification Initiative To cite this cell line use: HO-1-N-1 (RRID:CVCL_1284)
Comments Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX,Y
CSF1PO12
D13S31710,11
D16S5399,11
D5S8189
D7S82010,13
TH019
TPOX11
vWA16,18
Publications

CLPUB00049
Moroyama T., Miyauchi S., Akemi T., Sugata T., Takada K.
Establishment and characterization of a human tumor cell line (Nakata-1) derived from squamous carcinoma of the buccal mucosa.
Proc. Jpn. Cancer Assoc. 45:242-242(1986)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=17599052; DOI=10.1038/sj.onc.1210589
Suzuki E., Imoto I., Pimkhaokham A., Nakagawa T., Kamata N., Kozaki K.-I., Amagasa T., Inazawa J.
PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.
Oncogene 26:7921-7932(2007)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB0831
Cell line databases/resources CGH-DB; 372-2
Cosmic-CLP; 924111
GDSC; 924111
LINCS_LDP; LCL-1204
Ontologies BTO; BTO:0005771
Biological sample resources BioSample; SAMN03472524
Chemistry resources ChEMBL-Cells; CHEMBL3308743
ChEMBL-Targets; CHEMBL1075466
Gene expression databases GEO; GSM827187
GEO; GSM1669888
Polymorphism and mutation databases Cosmic; 924111
Cosmic; 1118793
Cosmic; 1120708
Cosmic; 1530741
Cosmic; 1571801
Cosmic; 2266787