Cellosaurus HT-3 (CVCL_1293)

Cell line name HT-3
Synonyms HT3
Accession CVCL_1293
Resource Identification Initiative To cite this cell line use: HT-3 (RRID:CVCL_1293)
Comments From: Memorial Sloan-Kettering Cancer Center; New York; USA.
Registration: Memorial Sloan-Kettering Cancer Center Office of Technology Development; SK 784-01.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Cervical carcinoma (NCIt: C9039)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; PubMed=25877200

Markers:
AmelogeninX
CSF1PO12
D13S31712
D16S53912,13
D18S5115
D19S43314
D21S1129
D2S133821
D3S135815
D5S81810,13
D7S8208,10
D8S117913,14
FGA21,22
Penta D12
Penta E11,12
TH016,7
TPOX8
vWA15,18
Web pages https://www.mskcc.org/research-advantage/support/technology/tangible-material/ht-3-human-cervical-cell-line
Publications

DOI=10.1007/978-1-4757-1647-4_5
Fogh J., Trempe G.L.
New human tumor cell lines.
(In) Human tumor cells in vitro; Fogh J. (eds.); pp.115-159; Springer; New York (1975)

PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)

PubMed=833871; DOI=10.1093/jnci/58.2.209
Fogh J., Wright W.C., Loveless J.D.
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
J. Natl. Cancer Inst. 58:209-214(1977)

PubMed=7459858
Rousset M., Zweibaum A., Fogh J.
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)

PubMed=6220172
Dracopoli N.C., Fogh J.
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)

PubMed=2990217
Yee C., Krishnan-Hewlett I., Baker C.C., Schlegel R., Howley P.M.
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.
Am. J. Pathol. 119:361-366(1985)

PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)

PubMed=1648218; DOI=10.1073/pnas.88.13.5523
Scheffner M., Munger K., Byrne J.C., Howley P.M.
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines.
Proc. Natl. Acad. Sci. U.S.A. 88:5523-5527(1991)

PubMed=15531914; DOI=10.1038/sj.onc.1208235
Baldus S.E., Schwarz E., Lohrey C., Zapatka M., Landsberg S., Hahn S.A., Schmidt D., Dienes H.-P., Schmiegel W.H., Schwarte-Waldhoff I.
Smad4 deficiency in cervical carcinoma cells.
Oncogene 24:810-819(2005)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; HTB-32
Cell line databases/resources Cosmic-CLP; 907068
GDSC; 907068
IGRhCellID; HT3
LINCS_LDP; LCL-1304
Ontologies CLO; CLO_0004286
EFO; EFO_0002204
Biological sample resources BioSample; SAMN03472916
Chemistry resources ChEMBL-Cells; CHEMBL3308745
ChEMBL-Targets; CHEMBL1075470
Gene expression databases GEO; GSM253299
GEO; GSM675735
GEO; GSM685442
GEO; GSM1669914
Polymorphism and mutation databases Cosmic; 760222
Cosmic; 809227
Cosmic; 846183
Cosmic; 907068
Cosmic; 925353
Cosmic; 928908
Cosmic; 1131521
Cosmic; 1193036
Cosmic; 1201774
Cosmic; 1995449
Cosmic; 2301540