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Cellosaurus HuO-3N1 (CVCL_1297)

[Text version]

Cell line name HuO-3N1
Synonyms HuO3N1; HUO3N1
Accession CVCL_1297
Resource Identification Initiative To cite this cell line use: HuO-3N1 (RRID:CVCL_1297)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Japanese.
Characteristics: Established from a xenograft established in a nude mice.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Mutation; HGNC; 11998; TP53; Simple; p.Ala76fs*73 (c.225_226insT); Zygosity=Heterozygous (CCLE; Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0
East Asian, North72.02
East Asian, South23.28
South Asian1.73
European, North1.15
European, South0.24
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; RCB; TKG


Run an STR similarity search on this cell line

PubMed=3862491; DOI=10.1097/00003086-198510000-00038
Yamane T.
Establishment and characterization of cell lines derived from a human osteosarcoma.
Clin. Orthop. Relat. Res. 199:261-271(1985)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cell line collections JCRB; JCRB0413
RCB; RCB2104
TKG; TKG 0452
Cell line databases/resources CCLE; HUO3N1_BONE
Cell_Model_Passport; SIDM00584
Cosmic-CLP; 909977
DepMap; ACH-002142
Ontologies BTO; BTO:0002431
CLO; CLO_0050099
Biological sample resources BioSample; SAMN03471625
Chemistry resources ChEMBL-Cells; CHEMBL3308818
ChEMBL-Targets; CHEMBL1075475
GDSC; 909977
PharmacoDB; HuO3N1_642_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM320824
GEO; GSM1669920
Other Wikidata; Q54896886
Polymorphism and mutation databases Cosmic; 909977
IARC_TP53; 21389
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number29