Cellosaurus IGR-1 (CVCL_1303)

Cell line name IGR-1
Synonyms IGR 1; IGR1
Accession CVCL_1303
Resource Identification Initiative To cite this cell line use: IGR-1 (RRID:CVCL_1303)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~75-100 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Melanoma (NCIt: C3224)
Derived from metastatic site: Groin lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): CLS; Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10
D13S31713
D16S53911,13
D18S5116 (CLS)
14,16 (PubMed=25877200)
D21S1132.2
D3S135814,17
D5S81810,11
D7S82010,11
D8S117910 (CLS)
10,14 (PubMed=25877200)
FGA23,24
Penta D10
Penta E7,11
TH017,9.3 (CLS)
9.3 (Cosmic-CLP; PubMed=25877200)
TPOX8
vWA17,18
Publications

PubMed=954556; DOI=10.1016/0014-2964(76)90033-5
Aubert C., Lagrange C., Rorsman H., Rosengren E.
Catechols in primary and metastatic human malignant melanoma cells in monolayer culture.
Eur. J. Cancer 12:441-445(1976)

PubMed=405430; DOI=10.1111/1523-1747.ep12496554
Foa C., Aubert C.
Cellular localization of tyrosinase in human malignant melanoma cell lines.
J. Invest. Dermatol. 68:369-378(1977)

PubMed=6929009; DOI=10.1093/jnci/64.5.1029
Aubert C., Rouge F., Galindo J.R.
Tumorigenicity of human malignant melanocytes in nude mice in relation to their differentiation in vitro.
J. Natl. Cancer Inst. 64:1029-1040(1980)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections CLS; 300219/p483_IGR-1
CLS; 300219-SF/p11286_IGR-1
DSMZ; ACC-236
Cell line databases/resources CLDB; cl2624
CCLE; IGR1_SKIN
Cosmic-CLP; 907169
GDSC; 907169
LINCS_LDP; LCL-1247
Ontologies CLO; CLO_0006669
Biological sample resources BioSample; SAMN03472901
Chemistry resources ChEMBL-Cells; CHEMBL3308749
ChEMBL-Targets; CHEMBL1075479
Gene expression databases GEO; GSM887157
GEO; GSM888229
GEO; GSM1669927
Polymorphism and mutation databases Cosmic; 907169
Cosmic; 2230115