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Cellosaurus IM-9 (CVCL_1305)

Cell line name IM-9
Synonyms IM 9; IM9; GM04680
Accession CVCL_1305
Resource Identification Initiative To cite this cell line use: IM-9 (RRID:CVCL_1305)
Comments Problematic cell line: Misidentified. Originally thought to be a myeloma cell line but is a B-lymphoblastoid cell line (PubMed=10516762).
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: ~45 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Bone marrow.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): ATCC; Cosmic-CLP; DSMZ; JCRB; KCLB

Markers:
AmelogeninX
CSF1PO10,11
D13S3179,11
D16S5399,13
D3S135814,18
D5S81813
D7S82011,12
FGA20,23
TH016,9.3 (ATCC; Cosmic-CLP; DSMZ; KCLB)
6,10 (JCRB)
TPOX11
vWA14,17
Publications

PubMed=7579375
Pellat-Deceunynck C., Amiot M., Bataille R., Van Riet I., Van Camp B., Omede P., Boccadoro M.
Human myeloma cell lines as a tool for studying the biology of multiple myeloma: a reappraisal 18 years after.
Blood 86:4001-4002(1995)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=10516762; DOI=10.1038/sj.leu.2401510
Drexler H.G., Dirks W.G., MacLeod R.A.F.
False human hematopoietic cell lines: cross-contaminations and misinterpretations.
Leukemia 13:1601-1607(1999)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=20454443; DOI=10.1155/2010/904767
Uphoff C.C., Denkmann S.A., Steube K.G., Drexler H.G.
Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human and other primate cell lines.
J. Biomed. Biotechnol. 2010:904767-904767(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=29892436; DOI=10.1098/rsos.172472
Shioda S., Kasai F., Watanabe K., Kawakami K., Ohtani A., Iemura M., Ozawa M., Arakawa A., Hirayama N., Kawaguchi E., Tano T., Miyata S., Satoh M., Shimizu N., Kohara A.
Screening for 15 pathogenic viruses in human cell lines registered at the JCRB Cell Bank: characterization of in vitro human cells by viral infection.
R. Soc. Open Sci. 5:172472-172472(2018)

Cross-references
Cell line collections ATCC; CCL-159
BCRC; 60115
Coriell; GM04680
DSMZ; ACC-117
ECACC; 86051302
ICLC; HTL99009
IZSLER; BS TCL 98
JCRB; IFO50025
JCRB; JCRB0024
KCLB; 10159
Cell line databases/resources CLDB; cl2635
CLDB; cl2636
CLDB; cl2637
CLDB; cl4962
CLDB; cl5210
CCLE; IM9_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
CCRID; 3111C0002000000064
Cosmic-CLP; 753563
GDSC; 753563
LINCS_LDP; LCL-1958
Lonza; 9
Ontologies BTO; BTO:0002897
CLO; CLO_0006703
CLO; CLO_0006705
CLO; CLO_0019036
Biological sample resources BioSample; SAMN03471460
BioSample; SAMN03472807
Chemistry resources ChEMBL-Cells; CHEMBL3307412
ChEMBL-Targets; CHEMBL614584
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1374572
GEO; GSM1669932
Other Wikidata; Q54897504
Polymorphism and mutation databases Cosmic; 753563
Cosmic; 888021
Cosmic; 919137