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Cellosaurus IST-MEL1 (CVCL_1308)

[Text version]

Cell line name IST-MEL1
Synonyms ISTMEL1
Accession CVCL_1308
Resource Identification Initiative To cite this cell line use: IST-MEL1 (RRID:CVCL_1308)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.49
Native American1.88
East Asian, North0
East Asian, South1.65
South Asian5.96
European, North29.45
European, South59.56
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; ICLC

Markers:
AmelogeninX (Cosmic-CLP)
X,Y (ICLC)
CSF1PO10,12
D5S81811,13
D7S8209,10
D13S3179,12
D16S53911,12
D21S1133.2,34.2
TH019
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ICLC; HTL01006
Cell line databases/resources CLDB; cl5539
CCLE; ISTMEL1_SKIN
Cell_Model_Passport; SIDM00225
Cosmic-CLP; 907172
DepMap; ACH-002143
LINCS_HMS; 50020
LINCS_LDP; LCL-1234
Ontologies CLO; CLO_0006969
Chemistry resources ChEMBL-Cells; CHEMBL3308290
ChEMBL-Targets; CHEMBL2366094
GDSC; 907172
PharmacoDB; ISTMEL1_669_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1669942
Other Wikidata; Q54898343
Polymorphism and mutation databases Cosmic; 907172
Entry history
Entry creation04-Apr-2012
Last entry updated19-Dec-2019
Version number22