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Cellosaurus IST-SL2 (CVCL_1314)

[Text version]

Cell line name IST-SL2
Accession CVCL_1314
Resource Identification Initiative To cite this cell line use: IST-SL2 (RRID:CVCL_1314)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.3
Native American0.72
East Asian, North0
East Asian, South0.93
South Asian4.5
European, North46.2
European, South47.35
Disease Small cell lung carcinoma (NCIt: C4917)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; ICLC

Markers:
AmelogeninX
CSF1PO10,11
D5S81811
D7S82010,12
D13S31710,13
D16S53911,12
D21S1129
TH016,9.3
TPOX10
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ICLC; HTL97010
Cell line databases/resources CLDB; cl2909
CCLE; ISTSL2_LUNG
Cell_Model_Passport; SIDM00230
Cosmic-CLP; 753565
DepMap; ACH-002145
GDSC; 753565
LINCS_LDP; LCL-1869
Ontologies CLO; CLO_0006975
Chemistry resources ChEMBL-Cells; CHEMBL3308871
ChEMBL-Targets; CHEMBL2366101
PharmacoDB; ISTSL2_673_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1669945
Other Wikidata; Q54898351
Polymorphism and mutation databases Cosmic; 753565
Cosmic; 1995458
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number22