Cell line name | KMOE-2 | ||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Synonyms | KMOE2; Kmoe2 | ||||||||||||||||||
Accession | CVCL_1332 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: KMOE-2 (RRID:CVCL_1332) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Population: Japanese. Doubling time: 24.2 hours (PubMed=6949905); ~40-50 hours (DSMZ). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Peripheral blood. | ||||||||||||||||||
Sequence variations | Heterozygous for NRAS p.Gln61Arg (c.182A>G) (ClinVar=VCV000013900) (CCLE; Cosmic-CLP).Homozygous for TP53 p.Val272Met (c.814G>A) (ClinVar=VCV000185814) (CCLE; Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
| ||||||||||||||||||
Disease | Erythroleukemia (NCIt: C7152) Acute erythroid leukemia (ORDO: Orphanet_318) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
| ||||||||||||||||||
Hierarchy | Children:
| ||||||||||||||||||
Originate from same individual | CVCL_W022 ! KMOE-1 | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 2Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; DSMZ Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=6949905; DOI=10.1007/BF00410534 DOI=10.1016/B978-0-12-221970-2.50457-5 PubMed=16408098; DOI=10.1038/sj.leu.2404081 PubMed=20164919; DOI=10.1038/nature08768 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | DSMZ; ACC-37 | ||||||||||||||||||
Cell line databases/resources | CLDB; cl3034
CCLE; KMOE2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE Cell_Model_Passport; SIDM01019 Cosmic-CLP; 907280 DepMap; ACH-002258 LINCS_LDP; LCL-1058 | ||||||||||||||||||
Ontologies | CLO; CLO_0007114 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03473322 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308236
ChEMBL-Targets; CHEMBL2366347 GDSC; 907280 PharmacoDB; KMOE2_757_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610 GEO; GSM1446748 GEO; GSM1669991 | ||||||||||||||||||
Other | Wikidata; Q54900132 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 787445
Cosmic; 907280 Cosmic; 975262 Cosmic; 1012079 Cosmic; 1465969 Cosmic; 2131542 Cosmic; 2306213 IARC_TP53; 21434 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 02-Jul-2020 | ||||||||||||||||||
Version number | 30 |