Cellosaurus KMOE-2 (CVCL_1332)

Cell line name KMOE-2
Synonyms Kmoe2
Accession CVCL_1332
Resource Identification Initiative To cite this cell line use: KMOE-2 (RRID:CVCL_1332)
Comments Doubling time: 24.2 hours (PubMed=6949905); ~40-50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Erythroleukemia (NCIt: C7152)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_W022 ! KMOE-1
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO9,12
D13S3178,11
D16S5399,11
D5S8188,10
D7S82010
TH016,9
TPOX9
vWA14,17
Publications

PubMed=6949905; DOI=10.1007/BF00410534
Okano H., Okamura J., Yagawa K., Tasaka H., Motomura S.
Human erythroid cell lines derived from a patient with acute erythremia.
J. Cancer Res. Clin. Oncol. 102:49-55(1981)

PubMed=16408098; DOI=10.1038/sj.leu.2404081
Quentmeier H., MacLeod R.A.F., Zaborski M., Drexler H.G.
JAK2 V617F tyrosine kinase mutation in cell lines derived from myeloproliferative disorders.
Leukemia 20:471-476(2006)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-37
Cell line databases/resources CLDB; cl3034
Cosmic-CLP; 907280
GDSC; 907280
LINCS_LDP; LCL-1058
Ontologies CLO; CLO_0007114
Biological sample resources BioSample; SAMN03473322
Chemistry resources ChEMBL-Cells; CHEMBL3308236
ChEMBL-Targets; CHEMBL2366347
Gene expression databases GEO; GSM1446748
GEO; GSM1669991
Polymorphism and mutation databases Cosmic; 787445
Cosmic; 907280
Cosmic; 975262
Cosmic; 1012079
Cosmic; 1465969
Cosmic; 2131542
Cosmic; 2306213