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Cellosaurus KNS-81-FD (CVCL_1336)

[Text version]

Cell line name KNS-81-FD
Synonyms KNS-81FD; KNS81FD
Accession CVCL_1336
Resource Identification Initiative To cite this cell line use: KNS-81-FD (RRID:CVCL_1336)
Comments Group: Serum/protein free medium cell line.
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Brain.
Sequence variations Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; None_reported; -; Zygosity=- (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American1.58
East Asian, North77.83
East Asian, South20.58
South Asian0
European, North0
European, South0
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2799 (KNS-81)
Sex of cell Male
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO9,12
D5S8189,12
D7S82011
D13S3179
D16S53910,12
TH017,9
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections JCRB; IFO50444
Cell line databases/resources CCLE; KNS81FD_CENTRAL_NERVOUS_SYSTEM
Cell_Model_Passport; SIDM01210
Cosmic-CLP; 924188
DepMap; ACH-002259
LINCS_LDP; LCL-1383
Biological sample resources BioSamples; SAMEA1284015
Chemistry resources ChEMBL-Cells; CHEMBL3308306
ChEMBL-Targets; CHEMBL2366203
GDSC; 924188
PharmacoDB; KNS81FD_776_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1669997
Other Wikidata; Q54900254
Polymorphism and mutation databases Cosmic; 924188
Cosmic; 2367534
IARC_TP53; 27561
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number26