Cell line name | KYSE-220 | ||||||||||||||||||
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Synonyms | KYSE 220; KYSE220; KY-220 | ||||||||||||||||||
Accession | CVCL_1359 | ||||||||||||||||||
Secondary accession | CVCL_9819 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: KYSE-220 (RRID:CVCL_1359) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Population: Japanese. Doubling time: 20.5 hours (PubMed=1728357). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Esophagus. | ||||||||||||||||||
Sequence variations | CDKN2A p.His83Tyr (c.247C>T) (p.Ala97Val; c.290C>T) (ClinVar=VCV000376307) (PubMed=9033652).TP53 p.Arg248Trp (c.742C>T) (ClinVar=VCV000012347) (PubMed=8575860). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Esophageal squamous cell carcinoma (NCIt: C4024) Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Male | ||||||||||||||||||
Age at sampling | 78Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; JCRB Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=1728357; DOI=10.1002/1097-0142(19920115)69:2<277::AID-CNCR2820690202>3.0.CO;2-C PubMed=7913084; DOI=10.1002/ijc.2910580224 PubMed=8575860; DOI=10.1002/(SICI)1097-0215(19960126)65:3<372::AID-IJC16>3.0.CO;2-C PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C PubMed=11092977; DOI=10.1111/j.1349-7006.2000.tb00895.x PubMed=15172977; DOI=10.1158/0008-5472.CAN-04-0172 PubMed=16045545; DOI=10.1111/j.0959-9673.2005.00431.x PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | JCRB; JCRB1086
JCRB; NIHS0365 - Discontinued | ||||||||||||||||||
Cell line databases/resources | CCLE; KYSE220_OESOPHAGUS
Cell_Model_Passport; SIDM00551 CGH-DB; 283-1 CGH-DB; 9232-4 Cosmic-CLP; 1240167 DepMap; ACH-002263 LINCS_LDP; LCL-1559 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03472505 | ||||||||||||||||||
Chemistry resources | GDSC; 1240167
PharmacoDB; KYSE220_804_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-3610
GEO; GSM827502 GEO; GSM1670019 | ||||||||||||||||||
Other | Wikidata; Q54900812 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 918530
Cosmic; 1043241 Cosmic; 1581076 Cosmic; 1995476 Cosmic; 2650633 Cosmic; 2698439 IARC_TP53; 7683 Progenetix; CVCL_1359 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 29-Oct-2020 | ||||||||||||||||||
Version number | 29 |