Cell line name | KYSE-50 | ||||||||||||||||||
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Synonyms | KYSE 50; KYSE50; KY-50 | ||||||||||||||||||
Accession | CVCL_1360 | ||||||||||||||||||
Secondary accession | CVCL_9821 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: KYSE-50 (RRID:CVCL_1360) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Population: Japanese. Doubling time: 28.2 hours (PubMed=1728357). Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. Derived from sampling site: Esophagus. | ||||||||||||||||||
Sequence variations | Homozygous for PTCH1 p.Glu539Ter (c.1615G>T) (CCLE; Cosmic-CLP).Heterozygous for RHOA p.Gly17Val (c.50G>T) (CCLE; Cosmic-CLP).Homozygous for TP53 p.Lys101Ter (c.301A>T) (CCLE; Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Esophageal squamous cell carcinoma (NCIt: C4024) Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Male | ||||||||||||||||||
Age at sampling | 58Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): Cosmic-CLP; JCRB Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=1728357; DOI=10.1002/1097-0142(19920115)69:2<277::AID-CNCR2820690202>3.0.CO;2-C PubMed=7913084; DOI=10.1002/ijc.2910580224 PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | JCRB; JCRB0189 | ||||||||||||||||||
Cell line databases/resources | CCLE; KYSE50_OESOPHAGUS
Cell_Model_Passport; SIDM00550 Cosmic-CLP; 1298222 DepMap; ACH-002264 LINCS_LDP; LCL-1560 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03471649 | ||||||||||||||||||
Chemistry resources | GDSC; 1298222
PharmacoDB; KYSE50_809_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-3610
GEO; GSM827503 GEO; GSM1670023 | ||||||||||||||||||
Other | Wikidata; Q54900832 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 918522
Cosmic; 929520 Cosmic; 1043238 Cosmic; 1123334 Cosmic; 1581069 Cosmic; 1876250 Cosmic; 1995477 Cosmic; 2395006 Cosmic; 2650628 Progenetix; CVCL_1360 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 12-Jan-2021 | ||||||||||||||||||
Version number | 28 |