Cellosaurus KYSE-50 (CVCL_1360)

Cell line name KYSE-50
Synonyms KYSE 50; KYSE50; KY-50
Accession CVCL_1360
Secondary accession CVCL_9821
Resource Identification Initiative To cite this cell line use: KYSE-50 (RRID:CVCL_1360)
Comments Doubling time: 28.2 hours (PubMed=1728357).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX
CSF1PO12 (Cosmic-CLP)
11,12 (JCRB)
D13S31711
D16S53910,12
D5S81811
D7S82010
TH018
TPOX11 (Cosmic-CLP)
10,11 (JCRB)
vWA17,19
Publications

PubMed=1728357; DOI=10.1002/1097-0142(19920115)69:2<277::AID-CNCR2820690202>3.0.CO;2-C
Shimada Y., Imamura M., Wagata T., Yamaguchi N., Tobe T.
Characterization of 21 newly established esophageal cancer cell lines.
Cancer 69:277-284(1992)

PubMed=7913084; DOI=10.1002/ijc.2910580224
Kanda Y., Nishiyama Y., Shimada Y., Imamura M., Nomura H., Hiai H., Fukumoto M.
Analysis of gene amplification and overexpression in human esophageal-carcinoma cell lines.
Int. J. Cancer 58:291-297(1994)

PubMed=9033652; DOI=10.1002/(SICI)1097-0215(19970207)70:4<437::AID-IJC11>3.0.CO;2-C
Tanaka H., Shimada Y., Imamura M., Shibagaki I., Ishizaki K.
Multiple types of aberrations in the p16 (INK4a) and the p15(INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines.
Int. J. Cancer 70:437-442(1997)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB0189
Cell line databases/resources Cosmic-CLP; 1298222
GDSC; 1298222
LINCS_LDP; LCL-1560
Biological sample resources BioSample; SAMN03471649
Gene expression databases GEO; GSM827503
GEO; GSM1670023
Polymorphism and mutation databases Cosmic; 918522
Cosmic; 929520
Cosmic; 1043238
Cosmic; 1123334
Cosmic; 1581069
Cosmic; 1876250
Cosmic; 1995477
Cosmic; 2395006