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Cellosaurus LB1047-RCC (CVCL_1364)

[Text version]

Cell line name LB1047-RCC
Synonyms LB1047RCC; LB1047
Accession CVCL_1364
Resource Identification Initiative To cite this cell line use: LB1047-RCC (RRID:CVCL_1364)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
From: Ludwig Institute for Cancer Research, Brussels Branch; Brussels; Belgium.
Microsatellite instability: Instable (MSI-high) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.9
Native American0
East Asian, North0.45
East Asian, South0
South Asian20.18
European, North20.14
European, South58.33
Disease Renal cell carcinoma (NCIt: C9385)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_E908 ! LB1047-EBV
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO11,13
D5S81812,13
D7S8209
D13S31711,12
D16S53911
TH017
TPOX8,10
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=10074909; DOI=10.1002/(SICI)1097-0215(19990315)80:6<799::AID-IJC1>3.0.CO;2-U
Dumas F., Gala J.-L., Berteau P., Brasseur F., Eschwege P., Paradis V., Lacour B., Philippe M., Loric S.
Molecular expression of PSMA mRNA and protein in primary renal tumors.
Int. J. Cancer 80:799-803(1999)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28489074; DOI=10.1038/ncomms15165
Sinha R., Winer A.G., Chevinsky M., Jakubowski C., Chen Y.-B., Dong Y., Tickoo S.K., Reuter V.E., Russo P., Coleman J.A., Sander C., Hsieh J.J., Hakimi A.A.
Analysis of renal cancer cell lines from two major resources enables genomics-guided cell line selection.
Nat. Commun. 8:15165-15165(2017)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; LB1047RCC_KIDNEY
Cell_Model_Passport; SIDM00187
Cosmic-CLP; 753577
DepMap; ACH-002150
GDSC; 753577
LINCS_LDP; LCL-1765
Chemistry resources ChEMBL-Cells; CHEMBL3308329
ChEMBL-Targets; CHEMBL2366136
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670033
Other Wikidata; Q54902027
Polymorphism and mutation databases Cosmic; 753577
Entry history
Entry creation04-Apr-2012
Last entry updated05-Jul-2019
Version number23