Home  |  Contact

Cellosaurus LB647-SCLC (CVCL_1368)

[Text version]

Cell line name LB647-SCLC
Synonyms LB647SCLC
Accession CVCL_1368
Resource Identification Initiative To cite this cell line use: LB647-SCLC (RRID:CVCL_1368)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
From: Ludwig Institute for Cancer Research, Brussels Branch; Brussels; Belgium.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Mutation; HGNC; 11998; TP53; Simple; p.Glu294Serfs*51 (c.880delG); Zygosity=Heterozygous (CCLE; Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.14
East Asian, North0
East Asian, South0.99
South Asian0.19
European, North66.53
European, South32.15
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VU82 ! LB647-PBL
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81812
D7S82012
D13S3179,13
D16S53911,12
TH019.3
TPOX8,11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; LB647SCLC_LUNG
Cell_Model_Passport; SIDM00183
Cosmic-CLP; 753582
DepMap; ACH-002154
LINCS_LDP; LCL-1870
Chemistry resources ChEMBL-Cells; CHEMBL3308332
ChEMBL-Targets; CHEMBL2366140
GDSC; 753582
PharmacoDB; LB647SCLC_824_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670037
Other Wikidata; Q54902076
Polymorphism and mutation databases Cosmic; 753582
Cosmic; 1995478
IARC_TP53; 21465
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number28