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Cellosaurus LB771-HNC (CVCL_1369)

[Text version]

Cell line name LB771-HNC
Synonyms LB771-HNSCC; LB771HNC; LB771-ORL
Accession CVCL_1369
Resource Identification Initiative To cite this cell line use: LB771-HNC (RRID:CVCL_1369)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
From: Ludwig Institute for Cancer Research, Brussels Branch; Brussels; Belgium.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.73
Native American0.55
East Asian, North0.07
East Asian, South0.71
South Asian0.51
European, North59.61
European, South37.83
Disease Head and neck squamous cell carcinoma (NCIt: C34447)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_VU87 ! LB771-PBL
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S8207,12
D13S31711,12
D16S53911,13
TH019.3
TPOX8
vWA19

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; LB771HNC_UPPER_AERODIGESTIVE_TRACT
Cell_Model_Passport; SIDM00182
Cosmic-CLP; 753583
DepMap; ACH-002265
GDSC; 753583
LINCS_LDP; LCL-1575
Chemistry resources ChEMBL-Cells; CHEMBL3308308
ChEMBL-Targets; CHEMBL2366099
PharmacoDB; LB771HNC_825_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670038
Other Wikidata; Q54902083
Polymorphism and mutation databases Cosmic; 753583
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number23