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Cellosaurus LC-1F (CVCL_1372)

[Text version]

Cell line name LC-1F
Synonyms LC1F; Lung cancer-1/squamous, floating variant
Accession CVCL_1372
Resource Identification Initiative To cite this cell line use: LC-1F (RRID:CVCL_1372)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Sequence variations Heterozygous for SPEN p.Arg1475Ter (c.4423C>T) (CCLE).
Homozygous for TP53 p.Met237Ile (c.711G>T) (CCLE).
Genome ancestry Source: PubMed=30894373

Origin% genome
African6.24
Native American0
East Asian, North88.7
East Asian, South0
South Asian0
European, North0
European, South5.06
Disease Squamous cell lung carcinoma (NCIt: C3493)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3008 (LC-1/sq)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): RCB

Markers:
AmelogeninX
CSF1PO12
D5S81812,13
D7S82012
D13S31712
D16S5399
TH017,9
TPOX8,12
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=24002593; DOI=10.1038/bjc.2013.452
Wu D., Pang Y., Wilkerson M.D., Wang D., Hammerman P.S., Liu J.S.
Gene-expression data integration to squamous cell lung cancer subtypes reveals drug sensitivity.
Br. J. Cancer 109:1599-1608(2013)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

Cross-references
Cell line collections RCB; RCB0439
Cell line databases/resources CCLE; LC1F_LUNG
Cell_Model_Passport; SIDM00298
DepMap; ACH-000705
GDSC; 907785
LINCS_LDP; LCL-1595
Ontologies CLO; CLO_0050026
EFO; EFO_0002827
Biological sample resources BioSample; SAMN03472313
BioSample; SAMN10988100
Chemistry resources ChEMBL-Cells; CHEMBL3308207
ChEMBL-Targets; CHEMBL2366216
PharmacoDB; LC1F_830_2019
Gene expression databases ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM1670041
Other Wikidata; Q54902123
Polymorphism and mutation databases Cosmic; 907785
Cosmic; 1995479
IARC_TP53; 21469
LiGeA; CCLE_913
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number22