ID   LC-1F
AC   CVCL_1372
SY   LC1F; Lung cancer-1/squamous, floating variant
DR   CLO; CLO_0050026
DR   EFO; EFO_0002827
DR   ArrayExpress; E-MTAB-783
DR   ArrayExpress; E-MTAB-2770
DR   ArrayExpress; E-MTAB-3610
DR   BioSample; SAMN03472313
DR   BioSample; SAMN10988100
DR   CCLE; LC1F_LUNG
DR   Cell_Model_Passport; SIDM00298
DR   ChEMBL-Cells; CHEMBL3308207
DR   ChEMBL-Targets; CHEMBL2366216
DR   Cosmic; 907785
DR   Cosmic; 1995479
DR   DepMap; ACH-000705
DR   GDSC; 907785
DR   GEO; GSM1670041
DR   IARC_TP53; 21469
DR   LiGeA; CCLE_913
DR   LINCS_LDP; LCL-1595
DR   PharmacoDB; LC1F_830_2019
DR   Progenetix; CVCL_1372
DR   RCB; RCB0439
DR   Wikidata; Q54902123
RX   PubMed=24002593;
RX   PubMed=30894373;
RX   PubMed=31068700;
CC   Part of: Cancer Cell Line Encyclopedia (CCLE) project.
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; 17575; SPEN; Simple; p.Arg1475Ter (c.4423C>T); Zygosity=Heterozygous (CCLE).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>T); ClinVar=VCV000634770; Zygosity=Homozygous (CCLE).
CC   Omics: Deep exome analysis.
CC   Omics: Deep RNAseq analysis.
CC   Omics: DNA methylation analysis.
CC   Omics: Transcriptome analysis.
CC   Genome ancestry: African=6.24%; Native American=0%; East Asian, North=88.7%; East Asian, South=0%; South Asian=0%; European, North=0%; European, South=5.06% (PubMed=30894373).
CC   Derived from sampling site: Lung.
ST   Source(s): RCB
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 12
ST   D16S539: 9
ST   D5S818: 12,13
ST   D7S820: 12
ST   TH01: 7,9
ST   TPOX: 8,12
ST   vWA: 17,18
DI   NCIt; C3493; Lung squamous cell carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens
HI   CVCL_3008 ! LC-1/sq
SX   Male
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 20-05-21; Version: 26
//
RX   PubMed=24002593; DOI=10.1038/bjc.2013.452;
RA   Wu D., Pang Y., Wilkerson M.D., Wang D., Hammerman P.S., Liu J.S.;
RT   "Gene-expression data integration to squamous cell lung cancer
RT   subtypes reveals drug sensitivity.";
RL   Br. J. Cancer 109:1599-1608(2013).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J., Gelfand E.T., Bielski C.M., Li H.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//