Cellosaurus LCLC-97TM1 (CVCL_1376)

Cell line name LCLC-97TM1
Synonyms LCLC97TM1
Accession CVCL_1376
Resource Identification Initiative To cite this cell line use: LCLC-97TM1 (RRID:CVCL_1376)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: >50 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep proteome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Misspelling: LCL97TM; In PubMed=26361996.
Disease Large cell lung carcinoma (NCIt: C4450)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): CLS; Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,11
D13S31711,13
D16S53912,13
D18S5116
D21S1127,30
D3S135815
D5S81811,12 (CLS)
10,12 (Cosmic-CLP; DSMZ; PubMed=25877200)
D7S82010,11 (CLS; Cosmic-CLP; DSMZ)
10,10.2,11 (PubMed=25877200)
D8S117914
FGA23
Penta D12,15
Penta E15
TH018
TPOX8,11
vWA19,20
Publications

PubMed=2840315; DOI=10.1111/j.1432-0436.1988.tb00806.x
Bepler G., Koehler A., Kiefer P., Havemann K., Beisenherz K., Jaques G., Gropp C., Haeder M.
Characterization of the state of differentiation of six newly established human non-small-cell lung cancer cell lines.
Differentiation 37:158-171(1988)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=26361996; DOI=10.1016/j.jprot.2015.09.003
Grundner-Culemann K., Dybowski J.N., Klammer M., Tebbe A., Schaab C., Daub H.
Comparative proteome analysis across non-small cell lung cancer cell lines.
J. Proteomics 130:1-10(2016)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections CLS; 300409/p504_LCLC-97TM1
DSMZ; ACC-388
Cell line databases/resources CCLE; LCLC97TM1_LUNG
Cosmic-CLP; 946361
GDSC; 946361
IGRhCellID; LCLC97TM1GEO
LINCS_LDP; LCL-1782
Ontologies CLO; CLO_0007283
EFO; EFO_0006635
Biological sample resources BioSample; SAMN03473042
BioSample; SAMN03473572
Chemistry resources ChEMBL-Cells; CHEMBL3308112
ChEMBL-Targets; CHEMBL1075489
Gene expression databases GEO; GSM434288
GEO; GSM784234
GEO; GSM887265
GEO; GSM888340
GEO; GSM1670046
Polymorphism and mutation databases Cosmic; 946361
Cosmic; 1146948
Cosmic; 1995482
Proteomic databases PRIDE; PXD002556