Cellosaurus Loucy (CVCL_1380)

Cell line name Loucy
Synonyms LOUCY
Accession CVCL_1380
Resource Identification Initiative To cite this cell line use: Loucy (RRID:CVCL_1380)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: ENCODE project common cell types; tier 3.
Doubling time: ~60 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: H3K9ac ChIP-seq epigenome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peripheral blood.
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; DSMZ

Markers:
AmelogeninX
CSF1PO11,12
D13S31711,13
D16S53911
D5S81812 (ATCC; Cosmic-CLP)
11,12 (DSMZ)
D7S8209,10
TH018,9.3
TPOX8,9
vWA16,17
Web pages http://genome.ucsc.edu/ENCODE/protocols/cell/human/Loucy_Bernstein_protocol.pdf
Publications

PubMed=19166587; DOI=10.1186/1756-8722-2-3
Quentmeier H., Schneider B., Rohrs S., Romani J., Zaborski M., MacLeod R.A.F., Drexler H.G.
SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines.
J. Hematol. Oncol. 2:3-3(2009)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=22675565; DOI=10.1371/journal.pone.0038463
Kalender Atak Z., De Keersmaecker K., Gianfelici V., Geerdens E., Vandepoel R., Pauwels D., Porcu M., Lahortiga I., Brys V., Dirks W.G., Quentmeier H., Cloos J., Cuppens H., Uyttebroeck A., Vandenberghe P., Cools J., Aerts S.
High accuracy mutation detection in leukemia on a selected panel of cancer genes.
PLoS ONE 7:E38463-E38463(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-2629
DSMZ; ACC-394
Cell line databases/resources CCLE; LOUCY_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cosmic-CLP; 907789
GDSC; 907789
LINCS_LDP; LCL-1017
Ontologies CLO; CLO_0007375
EFO; EFO_0007112
Biological sample resources BioSample; SAMN03471756
BioSample; SAMN03473575
ENCODE; ENCBS080PZG
ENCODE; ENCBS170DPY
ENCODE; ENCBS708EFA
Chemistry resources ChEMBL-Cells; CHEMBL3308208
ChEMBL-Targets; CHEMBL2366252
Gene expression databases GEO; GSM887272
GEO; GSM888347
GEO; GSM1670053
Polymorphism and mutation databases Cosmic; 907789
Cosmic; 913420
Cosmic; 1115598
Cosmic; 1151784
Cosmic; 1175133
Cosmic; 1330496
Cosmic; 1524802
Cosmic; 1641381
Cosmic; 1664525
Cosmic; 1760527
Cosmic; 2165717
Cosmic; 2602920