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Cellosaurus Lu-134-B (CVCL_1388)

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Cell line name Lu-134-B
Synonyms NCC-c-Lu-134-B-S; Lu-134-b; LU-134-B; LU-134B; Lu-134B; Lu134B
Accession CVCL_1388
Resource Identification Initiative To cite this cell line use: Lu-134-B (RRID:CVCL_1388)
Comments Doubling time: 57 hours (PubMed=3022030; PubMed=6098504).
Omics: SNP array analysis.
Sequence variations Heterozygous for PIK3CA p.Asp1029Tyr (c.3085G>T) (PubMed=19394761).
Disease Small cell lung carcinoma (NCIt: C4917)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_1387 ! Lu-134-A
Sex of cell Male
Age at sampling 80Y
Category Cancer cell line
STR profile Source(s): JCRB; RCB


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PubMed=6098504; DOI=10.20772/cancersci1959.75.12_1089
Terasaki T., Kameya T., Nakajima T., Tsumuraya M., Shimosato Y., Kato K., Ichinose H., Nagatsu T., Hasegawa T.
Interconversion of biological characteristics of small cell lung cancer depending on culture conditions.
Gann 75:1089-1099(1984)

Tsumuraya M., Nakajima T., Terasaki T., Kodama T., Shimosato Y., Higuchi H., Uei Y.
Analysis of LDH isoenzyme patterns in cell lines of the small cell carcinoma (lung) and retinoblastoma.
Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985)

Terasaki T., Shimosato Y., Nakajima T., Tsumuraya M., Morinaga S., Hirohashi S., Yamaguchi K., Kato K., Ichinose H., Nagatsu T.
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.
Jpn. J. Clin. Oncol. 16:203-212(1986)

PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7
Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T., Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S., Inazawa J.
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.
Am. J. Pathol. 161:207-216(2002)

PubMed=19394761; DOI=10.1016/j.canlet.2009.03.038
Shibata T., Kokubu A., Tsuta K., Hirohashi S.
Oncogenic mutation of PIK3CA in small cell lung carcinoma: a potential therapeutic target pathway for chemotherapy-resistant lung cancer.
Cancer Lett. 283:203-211(2009)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cell line collections JCRB; JCRB0169
JCRB; FDSC0038 - Discontinued
RCB; RCB0467
Cell line databases/resources Cell_Model_Passport; SIDM00295
CGH-DB; 90-1
CGH-DB; 9060-4
Ontologies BTO; BTO:0005439
CLO; CLO_0050029
Gene expression databases GEO; GSM827209
Other Wikidata; Q54903192
Polymorphism and mutation databases Cosmic; 1212194
Cosmic; 1571750
Entry history
Entry creation04-Apr-2012
Last entry updated25-Feb-2019
Version number17