ID   Lu-134-B
AC   CVCL_1388
SY   NCC-c-Lu-134-B-S; Lu-134-b; LU-134-B; LU-134B; Lu-134B; Lu134B
DR   BTO; BTO:0005439
DR   CLO; CLO_0050029
DR   cancercelllines; CVCL_1388
DR   Cell_Model_Passport; SIDM00295
DR   CGH-DB; 90-1
DR   CGH-DB; 9060-4
DR   Cosmic; 1212194
DR   Cosmic; 1571750
DR   GEO; GSM827209
DR   JCRB; JCRB0169
DR   JCRB; FDSC0038
DR   LINCS_LDP; LCL-1834
DR   Progenetix; CVCL_1388
DR   RCB; RCB0467
DR   Wikidata; Q54903192
RX   DOI=10.5795/jjscc.24.451;
RX   PubMed=3022030;
RX   PubMed=6098504;
RX   PubMed=12107105;
RX   PubMed=19394761;
RX   PubMed=20215515;
CC   Population: Japanese.
CC   Doubling time: 57 hours (PubMed=3022030; PubMed=6098504).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Asp1029Tyr (c.3085G>T); Zygosity=Heterozygous (PubMed=19394761).
CC   Omics: SNP array analysis.
CC   Discontinued: JCRB; FDSC0038; true.
CC   Derived from site: In situ; Lung; UBERON=UBERON_0002048.
ST   Source(s): JCRB; RCB
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 9
ST   D16S539: 9
ST   D5S818: 11
ST   D7S820: 11
ST   TH01: 9
ST   TPOX: 11
ST   vWA: 17
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_1387 ! Lu-134-A
SX   Male
AG   80Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 24
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RX   DOI=10.5795/jjscc.24.451;
RA   Tsumuraya M., Nakajima T., Terasaki T., Kodama T., Shimosato Y.,
RA   Higuchi H., Uei Y.;
RT   "Analysis of LDH isoenzyme patterns in cell lines of the small cell
RT   carcinoma (lung) and retinoblastoma.";
RL   Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985).
//
RX   PubMed=3022030; DOI=10.1093/oxfordjournals.jjco.a039144;
RA   Terasaki T., Shimosato Y., Nakajima T., Tsumuraya M., Morinaga S.,
RA   Hirohashi S., Yamaguchi K., Kato K., Ichinose H., Nagatsu T.;
RT   "Changes in cell characteristics due to culture conditions in cell
RT   lines from human small cell lung cancer.";
RL   Jpn. J. Clin. Oncol. 16:203-212(1986).
//
RX   PubMed=6098504; DOI=10.20772/cancersci1959.75.12_1089;
RA   Terasaki T., Kameya T., Nakajima T., Tsumuraya M., Shimosato Y.,
RA   Kato K., Ichinose H., Nagatsu T., Hasegawa T.;
RT   "Interconversion of biological characteristics of small cell lung
RT   cancer depending on culture conditions.";
RL   Gann 75:1089-1099(1984).
//
RX   PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7;
RA   Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T.,
RA   Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S.,
RA   Inazawa J.;
RT   "A novel target gene, SKP2, within the 5p13 amplicon that is
RT   frequently detected in small cell lung cancers.";
RL   Am. J. Pathol. 161:207-216(2002).
//
RX   PubMed=19394761; DOI=10.1016/j.canlet.2009.03.038;
RA   Shibata T., Kokubu A., Tsuta K., Hirohashi S.;
RT   "Oncogenic mutation of PIK3CA in small cell lung carcinoma: a
RT   potential therapeutic target pathway for chemotherapy-resistant lung
RT   cancer.";
RL   Cancer Lett. 283:203-211(2009).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458;
RA   Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P.,
RA   Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J.,
RA   Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C.,
RA   Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J.,
RA   Haber D.A.;
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//