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Cellosaurus Lu-139 (CVCL_1390)

Cell line name Lu-139
Synonyms NCC-c-Lu-139; LU-139; Lu139; LU139
Accession CVCL_1390
Resource Identification Initiative To cite this cell line use: Lu-139 (RRID:CVCL_1390)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 29 hours (PubMed=3022030).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Transcriptome analysis.
Disease Small cell lung carcinoma (NCIt: C4917)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX,Y
CSF1PO11
D5S81813
D7S82012
D13S31711
D16S5399
TH019
TPOX8,12
vWA17
Publications

PubMed=3022030
Terasaki T., Shimosato Y., Nakajima T., Tsumuraya M., Morinaga S., Hirohashi S., Yamaguchi K., Kato K., Ichinose H., Nagatsu T.
Changes in cell characteristics due to culture conditions in cell lines from human small cell lung cancer.
Jpn. J. Clin. Oncol. 16:203-212(1986)

PubMed=11005564; DOI=10.1038/sj.neo.7900094
Kohno T., Sato T., Takakura S., Takei K., Inoue K., Nishioka M., Yokota J.
Mutation and expression of the DCC gene in human lung cancer.
Neoplasia 2:300-305(2000)

PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7
Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T., Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S., Inazawa J.
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.
Am. J. Pathol. 161:207-216(2002)

PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections RCB; RCB0469
Cell line databases/resources CCLE; LU139_LUNG
CGH-DB; 93-1
CGH-DB; 9063-4
Cosmic-CLP; 713878
GDSC; 713878
LINCS_LDP; LCL-1872
Ontologies CLO; CLO_0050031
Biological sample resources BioSample; SAMN03472318
Chemistry resources ChEMBL-Cells; CHEMBL3308238
ChEMBL-Targets; CHEMBL2366248
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670065
Other Wikidata; Q54903195
Polymorphism and mutation databases Cosmic; 713878
Cosmic; 801607
Cosmic; 809123
Cosmic; 844822
Cosmic; 876156
Cosmic; 918007
Cosmic; 929158
Cosmic; 1212195
Cosmic; 1239931
Cosmic; 1571751
Cosmic; 1995495
Cosmic; 2125268
Cosmic; 2668340