Home  |  Contact

Cellosaurus Lu-165 (CVCL_1391)

[Text version]

Cell line name Lu-165
Synonyms LU-165; LU165
Accession CVCL_1391
Resource Identification Initiative To cite this cell line use: Lu-165 (RRID:CVCL_1391)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Indonesian.
Characteristics: Produces high level of vasopressin.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Heterozygous for PTEN p.Gly36Arg (c.106G>A) (CCLE; Cosmic-CLP).
Heterozygous for TP53 p.Val157Profs*9 (c.468_480delCGTCCGCGCCATG) (CCLE; Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
Native American0.53
East Asian, North28.73
East Asian, South70.74
South Asian0
European, North0
European, South0
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Derived from metastatic site: Lymph node.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB


Run an STR similarity search on this cell line
Web pages http://www.cellresource.cn/fdetail.aspx?id=604

PubMed=8071114; DOI=10.1111/j.1349-7006.1994.tb02420.x
Terasaki T., Matsuno Y., Shimosato Y., Yamaguchi K., Ichinose H., Nagatsu T., Kato K.
Establishment of a human small cell lung cancer cell line producing a large amount of anti-diuretic hormone.
Jpn. J. Cancer Res. 85:718-722(1994)

PubMed=12107105; DOI=10.1016/S0002-9440(10)64172-7
Yokoi S., Yasui K., Saito-Ohara F., Koshikawa K., Iizasa T., Fujisawa T., Terasaki T., Horii A., Takahashi T., Hirohashi S., Inazawa J.
A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.
Am. J. Pathol. 161:207-216(2002)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cell line collections RCB; RCB1184
Cell line databases/resources CCLE; LU165_LUNG
CCRID; 3131C0001000700034
Cell_Model_Passport; SIDM00292
CGH-DB; 99-1
CGH-DB; 9067-4
Cosmic-CLP; 753589
DepMap; ACH-002077
Ontologies CLO; CLO_0050069
Biological sample resources BioSample; SAMN03472172
Chemistry resources ChEMBL-Cells; CHEMBL3308239
ChEMBL-Targets; CHEMBL2366132
GDSC; 753589
PharmacoDB; LU165_868_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670066
Other Wikidata; Q54903204
Polymorphism and mutation databases Cosmic; 753589
Cosmic; 1212197
Cosmic; 1571740
Cosmic; 1995496
Cosmic; 2125173
IARC_TP53; 21481
Entry history
Entry creation04-Apr-2012
Last entry update12-Jan-2021
Version number28