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Cellosaurus MC-1010 (CVCL_1396)

[Text version]

Cell line name MC-1010
Synonyms MC1010
Accession CVCL_1396
Resource Identification Initiative To cite this cell line use: MC-1010 (RRID:CVCL_1396)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: SNP array analysis.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.31
Native American0.93
East Asian, North2.01
East Asian, South0
South Asian0
European, North60.99
European, South35.76
Disease Adult acute myeloid leukemia (NCIt: C9154)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11
D5S81811,14
D7S8208,12
D13S31711,12
D16S5399,13
TH016,9.3
TPOX8,11
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=167748; DOI=10.1016/0006-291X(75)90355-1
Chang S.C.-S., Bernofsky C.
Correlation between DNA synthesis and intracellular NAD in cultured human leukemic lymphocytes.
Biochem. Biophys. Res. Commun. 64:539-545(1975)

PubMed=8594420; DOI=10.1007/BF00928153
Bernofsky C., Bandara B.M.R.
Spin trapping endogenous radicals in MC-1010 cells: evidence for hydroxyl radical and carbon-centered ascorbyl radical adducts.
Mol. Cell. Biochem. 148:155-164(1995)

Patent=US5804443
Bernofsky C.
Human monocytic leukemia cell line.
Patent number US5804443, 08-Sep-1998

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ATCC; CRL-12253
Cell line databases/resources CCLE; MC1010_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM00009
Cosmic-CLP; 907798
DepMap; ACH-002390
GDSC; 907798
Chemistry resources PharmacoDB; MC1010_884_2019
Other Wikidata; Q54904166
Polymorphism and mutation databases Cosmic; 683546
Cosmic; 907798
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number15