ID   MC-1010
AC   CVCL_1396
SY   MC1010
DR   ArrayExpress; E-MTAB-783
DR   ATCC; CRL-12253
DR   cancercelllines; CVCL_1396
DR   Cell_Model_Passport; SIDM00009
DR   Cosmic; 683546
DR   Cosmic; 907798
DR   Cosmic-CLP; 907798
DR   DepMap; ACH-002390
DR   GDSC; 907798
DR   IARC_TP53; 21486
DR   PharmacoDB; MC1010_884_2019
DR   Wikidata; Q54904166
RX   Patent=US5804443;
RX   PubMed=167748;
RX   PubMed=8594420;
RX   PubMed=20164919;
RX   PubMed=30894373;
CC   Group: Patented cell line.
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: COSMIC cell lines project.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12253.
CC   Population: Caucasian.
CC   Microsatellite instability: Stable (MSS) (Sanger).
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Omics: Transcriptome analysis by microarray.
CC   Genome ancestry: African=0.31%; Native American=0.93%; East Asian, North=2.01%; East Asian, South=0%; South Asian=0%; European, North=60.99%; European, South=35.76% (PubMed=30894373).
ST   Source(s): Cosmic-CLP
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 9,13
ST   D5S818: 11,14
ST   D7S820: 8,12
ST   TH01: 6,9.3
ST   TPOX: 8,11
ST   vWA: 18
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 21
//
RX   Patent=US5804443;
RA   Bernofsky C.;
RT   "Human monocytic leukemia cell line.";
RL   Patent number US5804443, 08-Sep-1998.
//
RX   PubMed=167748; DOI=10.1016/0006-291X(75)90355-1;
RA   Chang S.C.-S., Bernofsky C.;
RT   "Correlation between DNA synthesis and intracellular NAD in cultured
RT   human leukemic lymphocytes.";
RL   Biochem. Biophys. Res. Commun. 64:539-545(1975).
//
RX   PubMed=8594420; DOI=10.1007/BF00928153;
RA   Bernofsky C., Bandara B.M.R.;
RT   "Spin trapping endogenous radicals in MC-1010 cells: evidence for
RT   hydroxyl radical and carbon-centered ascorbyl radical adducts.";
RL   Mol. Cell. Biochem. 148:155-164(1995).
//
RX   PubMed=20164919; DOI=10.1038/nature08768;
RA   Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S.,
RA   Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S.,
RA   Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T.,
RA   Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.;
RT   "Signatures of mutation and selection in the cancer genome.";
RL   Nature 463:893-898(2010).
//
RX   PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747;
RA   Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.;
RT   "An interactive resource to probe genetic diversity and estimated
RT   ancestry in cancer cell lines.";
RL   Cancer Res. 79:1263-1273(2019).
//