Cellosaurus SK-N-MC-IXC (CVCL_1398)

Cell line name SK-N-MC-IXC
Synonyms MC-IXC; MCIXC
Accession CVCL_1398
Resource Identification Initiative To cite this cell line use: SK-N-MC-IXC (RRID:CVCL_1398)
Comments From: Memorial Sloan-Kettering Cancer Center; New York; USA.
Registration: Memorial Sloan-Kettering Cancer Center Office of Technology Development; SK2010-067.
Microsatellite instability: Instable (MSI-low) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Askin tumor (NCIt: C7542)
Derived from metastatic site: Supra-orbital region.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0530 (SK-N-MC)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10
D13S31711
D16S53912
D18S5113,14,15
D19S43313,15.2
D21S1130,31.2
D2S133817,21
D3S135815
D5S81811
D7S8208
D8S117910
FGA21,25
Penta D9,13
Penta E16,18
TH019.3
TPOX9,11
vWA17,18
Web pages https://www.mskcc.org/research-advantage/support/technology/tangible-material/sk-n-mc-ixc-human-neuroblastoma-cell-line
Publications

PubMed=4748425
Biedler J.L., Helson L., Spengler B.A.
Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.
Cancer Res. 33:2643-2652(1973)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections ATCC; CRL-2270
Cell line databases/resources Cosmic-CLP; 908118
GDSC; 908118
IGRhCellID; MCIXC
LINCS_LDP; LCL-1967
TOKU-E; 4055
Ontologies BTO; BTO:0005372
CLO; CLO_0007615
EFO; EFO_0002230
Biological sample resources BioSample; SAMN03472918
Chemistry resources ChEMBL-Cells; CHEMBL3308758
ChEMBL-Targets; CHEMBL1075495
Gene expression databases GEO; GSM1670077
Polymorphism and mutation databases Cosmic; 688068
Cosmic; 908118