Cellosaurus MFE-280 (CVCL_1405)

Cell line name MFE-280
Synonyms MFE 280; MFE280
Accession CVCL_1405
Resource Identification Initiative To cite this cell line use: MFE-280 (RRID:CVCL_1405)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: MD Anderson Cell Lines Project.
Doubling time: ~60-90 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Endometrial adenocarcinoma (NCIt: C7359)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; ECACC

Markers:
AmelogeninX
CSF1PO9,12
D13S31710,12
D16S53912
D5S81811,12
D7S82010
TH017
TPOX9,10
vWA17
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=9620227; DOI=10.1007/s004320050122
Hackenberg R., Hawighorst T., Hild F., Schulz K.-D.
Establishment of new epithelial carcinoma cell lines by blocking monolayer formation.
J. Cancer Res. Clin. Oncol. 123:669-673(1997)

PubMed=9615781
Hackenberg R., Loos S., Nia A.H., Kunzmann R., Schulz K.-D.
Expression of placental protein 14 by the new endometrial cancer cell line MFE-280 in vitro and by endometrial carcinomas in vivo.
Anticancer Res. 18:1153-1158(1998)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections DSMZ; ACC-410
ECACC; 98050131
Cell line databases/resources CLDB; cl5080
CCLE; MFE280_ENDOMETRIUM
Cosmic-CLP; 908129
GDSC; 908129
LINCS_LDP; LCL-1500
Ontologies CLO; CLO_0007692
Biological sample resources BioSample; SAMN03473586
Chemistry resources ChEMBL-Cells; CHEMBL3308455
ChEMBL-Targets; CHEMBL1075502
Gene expression databases GEO; GSM374974
GEO; GSM375433
GEO; GSM844603
GEO; GSM887311
GEO; GSM888387
GEO; GSM1670098
Polymorphism and mutation databases Cosmic; 908129
Cosmic; 1434185
Cosmic; 1576462
Cosmic; 2030478