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Cellosaurus MFH-ino (CVCL_1407)

[Text version]

Cell line name MFH-ino
Synonyms MFH-INO
Accession CVCL_1407
Resource Identification Initiative To cite this cell line use: MFH-ino (RRID:CVCL_1407)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: 43 hours (at 41th passage), 32 hours (at 78th passage) (PubMed=1653597).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Has no TP53 mutation (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0
East Asian, North75.44
East Asian, South24.26
South Asian0.29
European, North0
European, South0
Disease Undifferentiated pleomorphic sarcoma (NCIt: C4247)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 45Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX
CSF1PO10
D5S81812
D7S8209,11
D13S31711
D16S53911
TH017,9
TPOX8,11
vWA16,19

Run an STR similarity search on this cell line
Publications

PubMed=1653597
Takahashi K., Sato K.
Establishment and characterization of a human neoplastic cell line (MFH-ino) derived from malignant fibrous histiocytoma of maxilla.
Hum. Cell 4:51-57(1991)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections RCB; RCB0749
Cell line databases/resources CCLE; MFHINO_SOFT_TISSUE
Cell_Model_Passport; SIDM00299
Cosmic-CLP; 925343
DepMap; ACH-002271
GDSC; 925343
LINCS_LDP; LCL-1753
Ontologies CLO; CLO_0050084
Biological sample resources BioSample; SAMN03472224
Chemistry resources ChEMBL-Cells; CHEMBL3308269
ChEMBL-Targets; CHEMBL2366262
PharmacoDB; MFHino_922_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM1670101
Other Wikidata; Q54905391
Polymorphism and mutation databases Cosmic; 925343
IARC_TP53; 27563
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number24