Cellosaurus MHH-NB-11 (CVCL_1412)

Cell line name MHH-NB-11
Synonyms MHH-NB11; MHHNB11
Accession CVCL_1412
Resource Identification Initiative To cite this cell line use: MHH-NB-11 (RRID:CVCL_1412)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Doubling time: ~100 hours (DSMZ).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Disease Neuroblastoma (NCIt: C3270)
Derived from metastatic site: Adrenal gland.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO12
D13S31712
D16S5399,13
D18S5116,17
D21S1130,31.2
D3S135815,17
D5S81811
D7S8208,9
D8S117913,14
FGA20,21
Penta D11,12
Penta E5,12
TH017,9.3
TPOX8
vWA16
Publications

PubMed=3218965
Pietsch T., Goettert E., Meese E., Blin N., Feickert H.-J., Riehm H., Kovacs G.
Characterization of a continuous cell line (MHH-NB-11) derived from advanced neuroblastoma.
Anticancer Res. 8:1329-1333(1988)

DOI=10.1016/B978-0-12-333530-2.50006-X
Israel M.A., Thiele C.J.
Tumor cell lines of the peripheral nervous system.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.43-78; Academic Press; New York (1994)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections DSMZ; ACC-157
Cell line databases/resources CLDB; cl3479
CCLE; MHHNB11_AUTONOMIC_GANGLIA
Cosmic-CLP; 908135
GDSC; 908135
LINCS_LDP; LCL-1975
Ontologies CLO; CLO_0007719
EFO; EFO_0006651
Biological sample resources BioSample; SAMN03473088
Chemistry resources ChEMBL-Cells; CHEMBL3308310
ChEMBL-Targets; CHEMBL2366185
Gene expression databases GEO; GSM887319
GEO; GSM888395
GEO; GSM1366409
GEO; GSM1670107
Polymorphism and mutation databases Cosmic; 908135
Cosmic; 2485948