Cellosaurus MHH-PREB-1 (CVCL_1413)

Cell line name MHH-PREB-1
Synonyms MHHPREB1
Accession CVCL_1413
Resource Identification Initiative To cite this cell line use: MHH-PREB-1 (RRID:CVCL_1413)
Comments Part of: MD Anderson Cell Lines Project.
Doubling time: ~20-40 hours (DSMZ).
Microsatellite instability: Instable (MSI-high) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Omics: SNP array analysis.
Derived from sampling site: Lymph node.
Disease B-cell non-Hodgkin lymphoma (NCIt: C3457)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; DSMZ; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO11
D13S3178,12
D16S5398,13
D18S5111,18
D21S1129,30
D3S135817,19
D5S81811,13,14 (Cosmic-CLP)
11,13 (DSMZ; PubMed=25877200)
D7S82011,12 (Cosmic-CLP; DSMZ)
11,12.3 (PubMed=25877200)
D8S117910,16
FGA21,23
Penta D9,13
Penta E7,16
TH017,9
TPOX9,11
vWA15,20
Web pages http://tcpaportal.org/mclp/
Publications

PubMed=9067587; DOI=10.1038/sj.leu.2400571
Uphoff C.C., MacLeod R.A.F., Denkmann S.A., Golub T.R., Borkhardt A., Janssen J.W.G., Drexler H.G.
Occurrence of TEL-AML1 fusion resulting from (12;21) translocation in human early B-lineage leukemia cell lines.
Leukemia 11:441-447(1997)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z., Liu H., Degenhardt J., Mayba O., Gnad F., Liu J., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W., Ju Z., Ling S., Vellano C.P., Roebuck P., Yu Q., Eterovic A.K., Byers L.A., Davies M.A., Deng W., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections DSMZ; ACC-354
Cell line databases/resources Cosmic-CLP; 908136
GDSC; 908136
IGRhCellID; MHHPREB1
LINCS_LDP; LCL-1140
Ontologies CLO; CLO_0007720
EFO; EFO_0002235
Biological sample resources BioSample; SAMN03471645
BioSample; SAMN03473315
Chemistry resources ChEMBL-Cells; CHEMBL3308334
ChEMBL-Targets; CHEMBL2366127
Gene expression databases GEO; GSM1670108
Polymorphism and mutation databases Cosmic; 908136
Cosmic; 2276316
Cosmic; 2491097