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Cellosaurus MLMA (CVCL_1419)

[Text version]

Cell line name MLMA
Accession CVCL_1419
Resource Identification Initiative To cite this cell line use: MLMA (RRID:CVCL_1419)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Doubling time: ~62 hours (lot 08272014) (JCRB).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Peritoneal effusion.
Genome ancestry Source: PubMed=30894373

Origin% genome
African0
Native American0.54
East Asian, North77.94
East Asian, South21.52
South Asian0
European, North0
European, South0
Disease Hairy cell leukemia (NCIt: C7402)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX
CSF1PO12,14
D5S81811
D7S82010
D13S3178,10
D16S5399,12
TH016,7
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections JCRB; JCRB0146
JCRB; NIHS0175 - Discontinued
Cell line databases/resources CCLE; MLMA_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE
Cell_Model_Passport; SIDM00561
Cosmic-CLP; 908142
DepMap; ACH-002274
GDSC; 908142
LINCS_LDP; LCL-1091
Biological sample resources BioSample; SAMN03470810
Chemistry resources ChEMBL-Cells; CHEMBL3308826
ChEMBL-Targets; CHEMBL2366211
PharmacoDB; MLMA_943_2019
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM827266
GEO; GSM1670117
Other Wikidata; Q54905976
Polymorphism and mutation databases Cosmic; 908142
Cosmic; 2690010
Entry history
Entry creation04-Apr-2012
Last entry updated06-Sep-2019
Version number24