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Cellosaurus MMAc-SF (CVCL_1420)

[Text version]

Cell line name MMAc-SF
Synonyms MMAC-SF; MMAc.SF; MMAc-Serum Free
Accession CVCL_1420
Resource Identification Initiative To cite this cell line use: MMAc-SF (RRID:CVCL_1420)
Comments Group: Serum/protein free medium cell line.
Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Population: Japanese.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Mutation; HGNC; 1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (CCLE; Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.62
Native American0.05
East Asian, North77.21
East Asian, South20.11
South Asian1.76
European, North0
European, South0.25
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5951 (MMAc)
Sex of cell Female
Age at sampling 39Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; RCB

Markers:
AmelogeninX
CSF1PO12
D5S81812
D7S82011
D13S3178,12
D16S5399,12
TH019
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections RCB; RCB1200
Cell line databases/resources CCLE; MMACSF_SKIN
Cell_Model_Passport; SIDM01242
Cosmic-CLP; 925339
DepMap; ACH-002162
LINCS_HMS; 50999
LINCS_LDP; LCL-1277
Ontologies CLO; CLO_0050088
Biological sample resources BioSample; SAMN03481114
Chemistry resources ChEMBL-Cells; CHEMBL3308270
ChEMBL-Targets; CHEMBL2366196
GDSC; 925339
PharmacoDB; MMACSF_945_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670119
Other Wikidata; Q54906202
Polymorphism and mutation databases Cosmic; 925339
IARC_TP53; 27564
Entry history
Entry creation04-Apr-2012
Last entry update20-May-2021
Version number27