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Cellosaurus MPP 89 (CVCL_1427)

[Text version]

Cell line name MPP 89
Synonyms MPP-89; MPP89
Accession CVCL_1427
Resource Identification Initiative To cite this cell line use: MPP 89 (RRID:CVCL_1427)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Derived from sampling site: Pleural effusion.
Genome ancestry Source: PubMed=30894373

Origin% genome
African5.06
Native American0
East Asian, North6.98
East Asian, South0
South Asian0
European, North33.57
European, South54.38
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S81811,12
D7S82011,12
D13S31713
D16S53911,13
TH018
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=10232421; DOI=10.1183/09031936.99.13352799
Orengo A.M., Spoletini L., Procopio A., Favoni R.E., De Cupis A., Ardizzoni A., Castagneto B., Ribotta M., Betta P.G., Ferrini S., Mutti L.
Establishment of four new mesothelioma cell lines: characterization by ultrastructural and immunophenotypic analysis.
Eur. Respir. J. 13:527-534(1999)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.K., Yu J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line collections ICLC; HTL00012
Cell line databases/resources CLDB; cl5400
CCLE; MPP89_PLEURA
Cell_Model_Passport; SIDM00222
Cosmic-CLP; 908150
GDSC; 908150
LINCS_LDP; LCL-1229
Ontologies CLO; CLO_0007858
Chemistry resources ChEMBL-Cells; CHEMBL3308241
ChEMBL-Targets; CHEMBL2366357
Gene expression databases ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610
GEO; GSM887341
GEO; GSM888417
GEO; GSM1670132
Other Wikidata; Q54906515
Polymorphism and mutation databases Cosmic; 908150
Cosmic; 1995512
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number22