Cellosaurus MRK-nu-1 (CVCL_1428)

Cell line name MRK-nu-1
Synonyms MRK-NU-1
Accession CVCL_1428
Resource Identification Initiative To cite this cell line use: MRK-nu-1 (RRID:CVCL_1428)
Comments Doubling time: ~47 hours (JCRB).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Disease Breast carcinoma (NCIt: C4872)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; JCRB

Markers:
AmelogeninX
CSF1PO9,10
D13S3178
D16S53910
D5S81813
D7S8208,10
TH016,9
TPOX11
vWA17,18
Publications

CLPUB00083
Sekiguchi M., Shiroko Y., Fujii G., Sudo K., Matsuzawa A., Suzuki K.
An ascites form of human mammary carcinoma transplantable in nude mice and isolation of two cell lines cultured in vitro.
Proc. Jpn. Cancer Assoc. 38:139-139(1979)

PubMed=9290701; DOI=10.1002/(SICI)1098-2744(199708)19:4<243::AID-MC5>3.0.CO;2-D
Jia L.-Q., Osada M., Ishioka C., Gamo M., Ikawa S., Suzuki T., Shimodaira H., Niitani T., Kudo T., Akiyama M., Kimura N., Matsuo M., Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.
Screening the p53 status of human cell lines using a yeast functional assay.
Mol. Carcinog. 19:243-253(1997)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cross-references
Cell line collections JCRB; JCRB0616 - Discontinued
JCRB; JCRB0628
Cell line databases/resources Cosmic-CLP; 908151
GDSC; 908151
LINCS_LDP; LCL-1487
Ontologies BTO; BTO:0003679
Biological sample resources BioSample; SAMN03471641
Chemistry resources ChEMBL-Cells; CHEMBL3308550
ChEMBL-Targets; CHEMBL2366325
Gene expression databases GEO; GSM827236
GEO; GSM1670133
Polymorphism and mutation databases Cosmic; 908151