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Cellosaurus SJNB-14 (CVCL_1444)

[Text version]

Cell line name SJNB-14
Synonyms SJNB14; NB14; NB14-DH; NCC
Accession CVCL_1444
Resource Identification Initiative To cite this cell line use: SJNB-14 (RRID:CVCL_1444)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Sequence variations Homozygous for TP53 c.376-1G>T; splice acceptor mutation (Cosmic-CLP).
Genome ancestry Source: PubMed=30894373

Origin% genome
African0.42
Native American0.13
East Asian, North0
East Asian, South0.23
South Asian5.64
European, North50.65
European, South42.92
Disease Neuroblastoma (NCIt: C3270)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y1M
Category Cancer cell line
STR profile Source(s): Cosmic-CLP

Markers:
AmelogeninX
CSF1PO12,13
D5S81812
D7S82012
D13S31711,12
D16S5399,12
TH019.3
TPOX10
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=922665; DOI=10.1002/1097-0142(197711)40:5<2256::AID-CNCR2820400536>3.0.CO;2-1
Brodeur G.M., Sekhon G., Goldstein M.N.
Chromosomal aberrations in human neuroblastomas.
Cancer 40:2256-2263(1977)

PubMed=6171342
Brodeur G.M., Green A.A., Hayes F.A., Williams K.J., Williams D.L., Tsiatis A.A.
Cytogenetic features of human neuroblastomas and cell lines.
Cancer Res. 41:4678-4686(1981)

PubMed=8516298; DOI=10.1073/pnas.90.12.5539
Johnson M.R., Look A.T., DeClue J.E., Valentine M.B., Lowy D.R.
Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
Proc. Natl. Acad. Sci. U.S.A. 90:5539-5543(1993)

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York (1999)

PubMed=10935473; DOI=10.1038/sj.neo.7900010
Kong X.-T., Valentine V.A., Rowe S.T., Valentine M.B., Ragsdale S.T., Jones B.G., Wilkinson D.A., Brodeur G.M., Cohn S.L., Look A.T.
Lack of homozygously inactivated p73 in single-copy MYCN primary neuroblastomas and neuroblastoma cell lines.
Neoplasia 1:80-89(1999)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z., Monteiro A.N., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

Cross-references
Cell line databases/resources CCLE; NB14_AUTONOMIC_GANGLIA
Cell_Model_Passport; SIDM00256
Cosmic-CLP; 949178
DepMap; ACH-002281
LINCS_LDP; LCL-1992
Ontologies BTO; BTO:0005073
Chemistry resources ChEMBL-Cells; CHEMBL3308827
ChEMBL-Targets; CHEMBL2366212
GDSC; 949178
PharmacoDB; NB14_988_2019
Gene expression databases ArrayExpress; E-MTAB-783
ArrayExpress; E-MTAB-3610
GEO; GSM1670149
Other Wikidata; Q54953558
Polymorphism and mutation databases Cosmic; 688072
Cosmic; 922663
Cosmic; 949178
Cosmic; 1526635
IARC_TP53; 27178
Entry history
Entry creation04-Apr-2012
Last entry updated19-Dec-2019
Version number26