Cellosaurus NB69 (CVCL_1448)

Cell line name NB69
Synonyms NB-69; NB_69; NB 69; NB69-RIKEN
Accession CVCL_1448
Resource Identification Initiative To cite this cell line use: NB69 (RRID:CVCL_1448)
Comments Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: SNP array analysis.
Disease Neuroblastoma (NCIt: C3270)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): Cosmic-CLP; ECACC; PubMed=25877200; RCB

Markers:
AmelogeninX,Y
CSF1PO11,12
D13S3178
D16S5399,11
D18S5115,16
D19S43314,15
D21S1130.2,31.2,32
D2S133817,23
D3S135816,17
D5S81811,12
D7S82010
D8S117913.2,14,15
FGA21,25
Penta D7,12
Penta E10,13
TH018
TPOX8,11 (Cosmic-CLP; PubMed=25877200; RCB)
11 (ECACC)
vWA17,18
Publications

DOI=10.1016/B978-0-12-333530-2.50006-X
Israel M.A., Thiele C.J.
Tumor cell lines of the peripheral nervous system.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.43-78; Academic Press; New York (1994)

DOI=10.1007/0-306-46872-7_2
Thiele C.J.
Neuroblastoma.
(In) Human cell culture. Vol. 1. Cancer Cell Lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York (1999)

PubMed=16822308; DOI=10.1186/1471-2407-6-177
Dam V., Morgan B.T., Mazanek P., Hogarty M.D.
Mutations in PIK3CA are infrequent in neuroblastoma.
BMC Cancer 6:177-177(2006)

PubMed=18923524; DOI=10.1038/nature07399
Chen Y., Takita J., Choi Y.L., Kato M., Ohira M., Sanada M., Wang L., Soda M., Kikuchi A., Igarashi T., Nakagawara A., Hayashi Y., Mano H., Ogawa S.
Oncogenic mutations of ALK kinase in neuroblastoma.
Nature 455:971-974(2008)

PubMed=23202128; DOI=10.1038/ng.2493
Sausen M., Leary R.J., Jones S., Wu J., Reynolds C.P., Liu X., Blackford A.L., Parmigiani G., Diaz L.A. Jr., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E., Hogarty M.D.
Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.
Nat. Genet. 45:12-17(2013)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

PubMed=28350380; DOI=10.1038/sdata.2017.33
Harenza J.L., Diamond M.A., Adams R.N., Song M.M., Davidson H.L., Hart L.S., Dent M.H., Fortina P., Reynolds C.P., Maris J.M.
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci. Data 4:170033-170033(2017)

Cross-references
Cell line collections ECACC; 99072802
RCB; RCB0480
Cell line databases/resources Cosmic-CLP; 908440
GDSC; 908440
LINCS_LDP; LCL-1999
Ontologies BTO; BTO:0005426
CLO; CLO_0050263
Biological sample resources BioSample; SAMN03470996
Chemistry resources ChEMBL-Cells; CHEMBL3308799
ChEMBL-Targets; CHEMBL1075510
Gene expression databases GEO; GSM313807
GEO; GSM563353
GEO; GSM827391
GEO; GSM1670154
GEO; GSM2371245
GEO; GSM2394385
Polymorphism and mutation databases Cosmic; 688081
Cosmic; 801739
Cosmic; 908440
Cosmic; 920248
Cosmic; 930069
Cosmic; 947709
Cosmic; 1019930
Cosmic; 1037342
Cosmic; 1099139
Cosmic; 1109123
Cosmic; 1153787
Cosmic; 1890119
Cosmic; 2058110
Cosmic; 2131577