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Cellosaurus NCC-IT (CVCL_1451)

Cell line name NCC-IT
Synonyms NCCIT
Accession CVCL_1451
Resource Identification Initiative To cite this cell line use: NCC-IT (RRID:CVCL_1451)
Comments Part of: Cancer Cell Line Encyclopedia (CCLE) project.
Part of: COSMIC cell lines project.
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Deep exome analysis.
Omics: DNA methylation analysis.
Misspelling: NCC15; In PubMed=24812411 and Cosmic 2163758.
Sequence variations MAP2K4 p.Lys309Asn (c.927G>C) (PubMed=9331070).
Disease Testicular embryonal carcinoma (NCIt: C6341)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_3045 (NCC-IT-A3)
Sex of cell Male
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): ATCC; Cosmic-CLP

Web pages https://de.wikipedia.org/wiki/NCC-IT_(Zelllinie)

Teshima S., Shimosato Y., Hirohashi S., Tome Y., Hayashi I., Kanazawa H., Kakizoe T.
Four new human germ cell tumor cell lines.
Lab. Invest. 59:328-336(1988)

Teng D.H.-F., Perry W.L. III, Hogan J.K., Baumgard M., Bell R., Berry S., Davis T., Frank D., Frye C., Hattier T., Hu R., Jammulapati S., Janecki T., Leavitt A., Mitchell J.T., Pero R., Sexton D., Schroeder M., Su P.-H., Swedlund B., Kyriakis J.M., Avruch J., Bartel P., Wong A.K.C., Oliphant A., Thomas A., Skolnick M.H., Tavtigian S.V.
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor.
Cancer Res. 57:4177-4182(1997)

PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
Iorio F., Knijnenburg T.A., Vis D.J., Bignell G.R., Menden M.P., Schubert M., Aben N., Goncalves E., Barthorpe S., Lightfoot H., Cokelaer T., Greninger P., van Dyk E., Chang H., de Silva H., Heyn H., Deng X., Egan R.K., Liu Q., Mironenko T., Mitropoulos X., Richardson L., Wang J., Zhang T., Moran S., Sayols S., Soleimani M., Tamborero D., Lopez-Bigas N., Ross-Macdonald P., Esteller M., Gray N.S., Haber D.A., Stratton M.R., Benes C.H., Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
A landscape of pharmacogenomic interactions in cancer.
Cell 166:740-754(2016)

Cell line collections ATCC; CRL-2073
BCRC; 60314
BCRJ; 0369
NCBI_Iran; C624
Cell line databases/resources CCLE; NCCIT_TESTIS
Cosmic-CLP; 908441
Ontologies BTO; BTO:0004180
CLO; CLO_0007955
Biological sample resources BioSample; SAMN03471433
Chemistry resources ChEMBL-Cells; CHEMBL3308379
ChEMBL-Targets; CHEMBL1075511
Gene expression databases GEO; GSM1670159
Other Wikidata; Q17578676
Polymorphism and mutation databases Cosmic; 687051
Cosmic; 908441
Cosmic; 1090412
Cosmic; 2077186
Cosmic; 2163758