Cell line name | NCI-H2066 | ||||||||||||||||||
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Synonyms | H2066; H-2066; NCIH2066 | ||||||||||||||||||
Accession | CVCL_1520 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: NCI-H2066 (RRID:CVCL_1520) | ||||||||||||||||||
Comments | Part of: Cancer Cell Line Encyclopedia (CCLE) project. Part of: COSMIC cell lines project. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: Deep RNAseq analysis. Omics: DNA methylation analysis. Omics: SNP array analysis. Omics: Transcriptome analysis. | ||||||||||||||||||
Sequence variations | Homozygous for TP53 p.Val157Phe (c.469G>T) (PubMed=1311061; CCLE; Cosmic-CLP). | ||||||||||||||||||
Genome ancestry | Source: PubMed=30894373
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Disease | Squamous cell lung carcinoma (NCIt: C3493) | ||||||||||||||||||
Species of origin | Homo sapiens (Human)
(NCBI Taxonomy: 9606)
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Sex of cell | Female | ||||||||||||||||||
Age at sampling | 70Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Publications | PubMed=1311061 PubMed=8806092; DOI=10.1002/jcb.240630505 PubMed=11030152; DOI=10.1038/sj.onc.1203815 PubMed=22460905; DOI=10.1038/nature11003 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections | ATCC; CRL-5917
KCLB; 92066 - Discontinued | ||||||||||||||||||
Cell line databases/resources | CCLE; NCIH2066_LUNG
Cell_Model_Passport; SIDM00711 Cosmic-CLP; 1330973 DepMap; ACH-000727 GDSC; 1330973 | ||||||||||||||||||
Ontologies | CLO; CLO_0008044 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03472599
BioSample; SAMN10987642 | ||||||||||||||||||
Chemistry resources | PharmacoDB; NCIH2066_1060_2019 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-2770
ArrayExpress; E-MTAB-3610 GEO; GSM434788 GEO; GSM887399 GEO; GSM888477 GEO; GSM1374718 GEO; GSM1670210 | ||||||||||||||||||
Other | Wikidata; Q54907910 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 2699647
IARC_TP53; 511 LiGeA; CCLE_647 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry updated | 06-Sep-2019 | ||||||||||||||||||
Version number | 21 |