Cellosaurus NCI-H378 (CVCL_1560)
Cell line name | NCI-H378 | ||||||||||||||||||
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Synonyms | H378; H-378; NCIH378 | ||||||||||||||||||
Accession | CVCL_1560 | ||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: NCI-H378 (RRID:CVCL_1560) | ||||||||||||||||||
Comments | Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: COSMIC cell lines project. Part of: MD Anderson Cell Lines Project. Population: Caucasian. Microsatellite instability: Stable (MSS) (Sanger). Omics: Deep exome analysis. Omics: DNA methylation analysis. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175. | ||||||||||||||||||
Sequence variations |
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Genome ancestry | Source: PubMed=30894373
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Disease | Lung small cell carcinoma (NCIt: C4917) Small cell lung cancer (ORDO: Orphanet_70573) | ||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
Originate from same individual | CVCL_A560 ! NCI-H379 | ||||||||||||||||||
Sex of cell | Female | ||||||||||||||||||
Age at sampling | 66Y | ||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||
STR profile | Source(s): ATCC; Cosmic-CLP Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
Web pages | https://tcpaportal.org/mclp/ | ||||||||||||||||||
Publications | PubMed=2985257 PubMed=8806092; DOI=10.1002/jcb.240630505 PubMed=8806103; DOI=10.1002/jcb.240630516 PubMed=10037197 PubMed=11030152; DOI=10.1038/sj.onc.1203815 PubMed=20164919; DOI=10.1038/nature08768 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112 PubMed=27397505; DOI=10.1016/j.cell.2016.06.017 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005 PubMed=30038707; DOI=10.18632/oncotarget.25642 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31803961; DOI=10.1002/jcb.29564 | ||||||||||||||||||
Cross-references | |||||||||||||||||||
Cell line collections (Providers) | ATCC; CRL-5808
KCLB; 90378 | ||||||||||||||||||
Cell line databases/resources | CLO; CLO_0008086
cancercelllines; CVCL_1560 Cell_Model_Passport; SIDM00915 Cosmic-CLP; 688022 DepMap; ACH-002173 IGRhCellID; NCIH378 | ||||||||||||||||||
Biological sample resources | BioSample; SAMN03471741 | ||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308295
ChEMBL-Targets; CHEMBL2366088 GDSC; 688022 PharmacoDB; NCIH378_1111_2019 PubChem_Cell_line; CVCL_1560 | ||||||||||||||||||
Encyclopedic resources | Wikidata; Q54908046 | ||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-783 ArrayExpress; E-MTAB-3610 GEO; GSM171878 GEO; GSM171879 GEO; GSM794286 GEO; GSM845546 GEO; GSM844649 GEO; GSM1670242 | ||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 688022
Cosmic; 850428 Cosmic; 877207 Cosmic; 877356 Cosmic; 980932 Cosmic; 1021861 Cosmic; 1032398 Cosmic; 1152468 Cosmic; 1995576 IARC_TP53; 21572 Progenetix; CVCL_1560 | ||||||||||||||||||
Sequence databases | EGA; EGAS00001000978 | ||||||||||||||||||
Entry history | |||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||
Last entry update | 30-Jan-2024 | ||||||||||||||||||
Version number | 35 |