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Cellosaurus NCI-H719 (CVCL_1582)

[Text version]

Cell line name NCI-H719
Synonyms H719; H-719
Accession CVCL_1582
Resource Identification Initiative To cite this cell line use: NCI-H719 (RRID:CVCL_1582)
Comments Part of: Small cell lung cancer p53 hotspot mutation cell panel (ATCC TCP-2040).
Omics: SNP array analysis.
Sequence variations Homozygous for TP53 p.Arg248Gln (c.743G>A) (ATCC).
Disease Small cell lung carcinoma (NCIt: C4917)
Derived from metastatic site: Bone marrow.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
STR profile Source(s): ATCC; KCLB

Markers:
AmelogeninX
CSF1PO10,11
D3S135814
D5S81813
D7S82010
D13S31712
D16S5399
FGA20
TH018,9
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=8806092; DOI=10.1002/jcb.240630505
Phelps R.M., Johnson B.E., Ihde D.C., Gazdar A.F., Carbone D.P., McClintock P.R., Linnoila R.I., Matthews M.J., Bunn P.A. Jr., Carney D.N., Minna J.D., Mulshine J.L.
NCI-Navy Medical Oncology Branch cell line data base.
J. Cell. Biochem. 63 Suppl. 24:32-91(1996)

PubMed=8806103; DOI=10.1002/jcb.240630516
Johnson B.E., Russell E., Simmons A.M., Phelps R.M., Steinberg S.M., Ihde D.C., Gazdar A.F.
MYC family DNA amplification in 126 tumor cell lines from patients with small cell lung cancer.
J. Cell. Biochem. 63 Suppl. 24:210-217(1996)

PubMed=11030152; DOI=10.1038/sj.onc.1203815
Modi S., Kubo A., Oie H., Coxon A.B., Rehmatulla A., Kaye F.J.
Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer.
Oncogene 19:4632-4639(2000)

PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)

Cross-references
Cell line collections ATCC; CRL-5837
KCLB; 90719
Cell line databases/resources GDSC; 924242
LINCS_LDP; LCL-1860
Ontologies CLO; CLO_0008109
Biological sample resources BioSample; SAMN03471750
Chemistry resources ChEMBL-Cells; CHEMBL3308551
ChEMBL-Targets; CHEMBL2366184
Other Wikidata; Q54908111
Polymorphism and mutation databases Cosmic; 688028
Cosmic; 844558
Cosmic; 877362
Cosmic; 924242
Cosmic; 980934
Cosmic; 1032401
Cosmic; 1152474
Cosmic; 2125256
IARC_TP53; 27194
Entry history
Entry creation04-Apr-2012
Last entry updated24-May-2019
Version number20